From: cornell.edu Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical …
Omega-6 Fatty Acid Promotes the Growth of an Aggressive Type of Breast Cancer
From: cornell.edu Linoleic acid, an omega-6 fatty acid found in seed oils such as soybean and safflower oil, and animal products including pork and eggs, specifically enhances the growth of the hard-to-treat “triple negative” breast cancer subtype, according to a preclinical study led by Weill Cornell Medicine investigators. The discovery could lead to new dietary and pharmaceutical strategies against breast …
Combination Radiation with Immunotherapy Shows Promise Against “Cold” Breast Cancer Tumors
From: news.weill.cornell.edu Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy—one that boosts T cells, and another that boosts dendritic cells—can control tumors in preclinical models of triple negative breast cancer, a cancer type that’s typically resistant to immunotherapy alone. Immunotherapy activates the body’s own immune system to fight cancer but isn’t effective …
Reducing copper in the body alters cancer metabolism to reduce risk of aggressive breast cancer
Source: Weill Cornell Medicine Depleting copper levels may reduce the production of energy that cancer cells need to travel and establish themselves in other parts of the body by a process referred to as metastasis, according to a new study by investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK). The discovery of the underlying mechanisms of …
Gold nanoparticle delivery of microRNA impairs metastasis in triple-negative breast cancer
By: Weill Cornell Medical College From: medicalxpress.com Weill Cornell Medicine researchers have shown that giving mice with triple-negative breast cancer therapeutic microRNA (miRNA) in a protective gold nanoparticle results in significantly less spreading of cancer to the lung. Triple-negative breast cancer is a highly aggressive, difficult-to-treat form of the disease, with a high rate of metastatic recurrence. miR-708 is a …
Slender women have a HIGHER risk of breast cancer, study warns
By: Mia De Graaf From: dailymail.co.uk Slender women have a higher risk of developing breast cancer, a new study warns. Scientists evaluated fat tissue from the breast and blood samples of 72 women with normal body-mass indices – less than 25. They found that 40 percent of them had ominous inflammation in their breast fat tissue. The reason, they believe, …