By Elizabeth Fernandez From: ucsf.edu A pioneering study has found that an individualized approach to breast cancer screening that assesses patients’ risk, rather than automatically giving annual mammograms, can lower the chance of more advanced cancers, while still safely matching people to the amount of screening they need. The results — which come from 46,000 U.S. women enrolled in the …
Breast Cancer Riddle: Best Ways to Screen and Treat
By: Elizabeth Fernandez From: ucsf.edu Despite decades of scientific progress, breast cancer remains the most common cancer among women in the United States. Experts are divided on many aspects, such as when and how often to do mammograms, how to rethink interventions for precancer lesions, and how to pinpoint risk and reduce the toxicity of treatments. During Breast Cancer Awareness …
“Smarter” breast cancer screening measures risk down to your DNA
By: Elizabeth Fernandez, UC San Francisco From: universityofcalifornia.edu A novel UC San Francisco study that aims to transform breast cancer screening is expanding to reach women as young as 30, with the intention of including thousands of women who could be at higher risk of developing aggressive cancer. The expanded study, known as WISDOM 2.0, is testing a personalized approach …
UCSF and I-SPY 2 Breast Cancer Researchers Develop Newly Redefined Breast Cancer Response Subtypes
Source Quantum Leap Healthcare Collaborative From: PR Newswire Improved Classifications May Increase Precision in Targeted Therapies Research scientists and statisticians from UC San Francisco have developed improved biomarker classifications as part of their research results in the I-SPY 2 trial for high-risk breast cancer patients. The new cancer response subtypes reflect responsiveness to drug treatments and are intended to help …
An Estrogen Receptor that Promotes Cancer also Causes Drug Resistance
By: Laura Kurtzman From: ucsf.edu UCSF Researchers Discover New Role for Erα as an RNA-Binding Protein Cancer cells proliferate despite a myriad of stresses – from oxygen deprivation to chemotherapy – that would kill any ordinary cell. Now, researchers at UC San Francisco have gained insight into how they may be doing this through the downstream activity of a powerful …
Keytruda and Chemotherapy Combination Broadens Number of Treatable Patients with TNBC
By: Conor Killmurray From: curetoday.com In an interview with CURE®, lead study investigator of the Keynote 355 trial, Dr. Hope S Rugo, discusses the results of the study that led to the FDA approval of the combination therapy and what further data means for certain patients with metastatic triple-negative breast cancer. In November, the Food and Drug Administration (FDA) granted …
Breast Cancer Subtypes Vary With Indigenous Ancestry in Latin American Women
By: Staff Reporter From: precisiononcologynews.com Breast cancer patients with a greater proportion of Indigenous American genetic ancestry appear more prone to having tumors of the HER2-positive subtype, according to new research from the University of California, San Francisco and elsewhere, though additional work is needed to tease out potential genetic contributors to this propensity. “The association between IA ancestry and …
Gene test can reduce chemo use among breast-cancer patients, study says
By: Laurie McGinley From: washingtonpost.com Doctors have long known that many early-stage breast cancer patients who undergo chemotherapy don’t actually need it to prevent recurrence of the disease after surgery. But they haven’t known exactly which patients might safely skip the toxic treatment. A European study published Wednesday in the New England Journal of Medicine sheds new light on the …
Stunning cancer discovery could change treatments
By: Dan Taylor From: morningticker.com A stunning new report on colon cancer could result in breakthroughs in new treatments. A study found that the survival odds against colon cancer depend a lot on which side of your colon the tumor develops, which could provide new insights into how the cancer grows and therefore what could potentially stop it, according to …
New device helps cancer patients prevent hair loss
By: Tim Didion From: abc7news.com It’s been four years since Rebecca Yarnold survived a harrowing fight with breast cancer. And even during chemotherapy, she kept her spirits up and shield her young son from the anxiety, in part by keeping her hair. “I was able to function, and because I had my hair it didn’t scare him,” Yarnold said. Yarnold …
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