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Chemotherapy linked to physical decline in older women with high-risk breast cancer

In In The News by Barbara Jacoby

Source: University of California – Los Angeles Health Sciences From: news-medical.net A UCLA-led study suggests women who are 65 years old or older with high-risk breast cancer and are treated with chemotherapy are more likely to develop a substantial decline in physical function. The study, published in a special issue of the Journal of Cancer Survivorship, found over 30% of older …

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This revolutionary breast cancer drug has saved millions of lives in its 25-year history

In In The News by Barbara Jacoby

By: Dennis J. Slamon, MD (FEL ’82), PhD From: uclahealth.org In the early 1990s, women who were diagnosed with the HER2-positive subtype of breast cancer weren’t expected to live more than three-to-five years after diagnosis. Now, depending on the stage of the cancer at diagnosis, women with HER2-positive breast cancer have among the highest survival rates of all women with …

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Updated results on a new approach to treating advanced ER-positive/HER2-negative breast cancer

In In The News by Barbara Jacoby

Source: University of California – Los Angeles Health Sciences From: news-medical.net A UCLA Jonsson Comprehensive Cancer Center researcher and collaborators in a multicenter study will present updated results and plans for further research on a new approach to treating advanced ER-positive/HER2-negative breast cancer. The study is the first-in-human, open-label, three-part study of ARV-471, alone or in combination with the drug …

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Breaking down barriers to care for metastatic breast cancer patients

In In The News by Barbara Jacoby

From: Elaiza Torralba From: ucla.edu UCLA team recommends state-level policy changes to improve health insurance coverage, participation in clinical trials and access to palliative care Drawing on a series of studies and interviews with patients and caregivers, UCLA researchers from the UCLA Center for Health Policy Research and the UCLA Jonsson Comprehensive Cancer Center have published recommendations for California policymakers and patient …

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Mindfulness Meditation, Survivorship Education Reduce Depression in Young Breast Cancer Survivors

In In The News by Barbara Jacoby

By: Kristie L. Kahl From: cancernetwork.com Behavioral interventions, including mindfulness meditation and survivorship education classes, reduced depressive symptoms in younger women treated for breast cancer, according to study findings presented at the 2020 San Antonio Breast Cancer Symposium. Approximately 20% of breast cancers occur in women aged 50 or younger, a group of patients who are at an increased risk …

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Engineered killer T cells could provide long-lasting immunity against cancer

In In The News by Barbara Jacoby

UCLA researchers use stem cells to engineer cells that attack human tumors in mice They’ve been called the “special forces” of the immune system: invariant natural killer T cells. Although there are relatively few of them in the body, they are more powerful than many other immune cells. In experiments with mice, UCLA researchers have shown they can harness the …

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Drug accelerates blood system’s recovery after chemotherapy, radiation

In In The News by Barbara Jacoby

From: ucla.edu A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants. The study, published in Nature Communications, also sheds light on the basic biology …

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Personalized gene-edited immune cell therapy for patients with solid cancers: New data establishes approach for verifying patient-specific cancer mutation targets

In Clinical Studies News by Barbara Jacoby

Source: PACT Pharma From: PR Newswire – PACT’s gene-edited T cells were observed to kill tumor cells by targeting patient-specific tumor mutation targets in non-clinical testing – The company is launching clinical studies of personalized targeted immune cell therapy for patients with solid cancers PACT Pharma, a leader in the fields of cancer immunology and cell therapy in collaboration with …

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Adding targeted therapy to treatment extends lives of those with metastatic breast cancer

In Clinical Studies News by Barbara Jacoby

Source: UCLA Jonsson Comprehensive Cancer Center From: eurekalert.org A UCLA-led study has found that using a drug called ribociclib in combination with a common hormone therapy may help premenopausal women with the most common type of breast cancer live longer than if they only receive the hormone therapy. Ribociclib is considered a cyclin-dependent kinase inhibitor that works by blocking the …

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Science Says: Chemo Brain Is Real.

In In The News by Barbara Jacoby

UCLA Study Shows Breast Cancer Treatments Can Cause Cognitive Impairment By: Brittany Shoot From: fortune.com A new study from researchers at the University of California, Los Angeles shows that some cancer patients can experience cognitive decline after chemotherapy and radiation treatments. It’s commonly thought that cancer treatments may accelerate biological aging in cells. Specifically seen in this new UCLA study …