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Which First-Line Breast Cancer Therapy Is Right for Me?

In In The News by Barbara Jacoby

From: healthline.com Knowing where to turn next with your breast cancer treatment can be a tough decision. But understanding the different types of therapies available for metastatic breast cancer can help ensure you know what’s best for you. Hormone and targeted therapies Hormonal therapies The first-line treatment for advanced hormone receptor-positive (estrogen receptor-positive or progesterone receptor-positive) breast cancer is usually …

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Managing HER2+ Early Breast Cancer: A Focus on Target Therapy

In In The News by Barbara Jacoby

From: targetedonc.com New breast cancer diagnoses account for 31% of annual cancer diagnoses among women in the United States.1 Among those diagnoses, HER2 overexpression is observed in 25% to 30% of cases. Historically, HER2-positive (HER2+) breast cancer was considered an aggressive subtype and was associated with a poor prognosis; however, the emergence of HER2-targeted therapies such as trastuzumab has considerably …

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Moffitt Researchers Identify Pathway that Controls Breast Cancer Metastasis to the Brain

In In The News by Barbara Jacoby

From: moffitt.org Breast cancer is the second most common cause of brain metastasis, which occurs in 10% to 30% of patients with metastatic breast cancer. Breast cancer patients who develop brain metastasis have limited treatment options and poor survival. Moffitt Cancer Center researchers are working to better understand the molecular mechanisms that promote the development and progression of breast cancer …

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AI may spare breast cancer patients unnecessary treatments

In In The News by Barbara Jacoby

By: Northwestern University From: medicalxpress.com A new AI (artificial intelligence) tool may make it possible to spare breast cancer patients unnecessary chemotherapy treatments by using a more precise method of predicting their outcomes, reports a new Northwestern Medicine study. AI evaluations of patient tissues were better at predicting the future course of a patient’s disease than evaluations performed by expert …

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First-Line Treatments for HER2-Positive Breast Cancer

In In The News by Barbara Jacoby

By: Hatem Soliman, MD From: targetedonc.com Hatem Soliman, MD, medical oncologist in The Center for Women’s Oncology and assistant member of the Experimental Therapeutics Program at Moffitt Cancer Center, discusses the current first-line treatment options for patients with HER2-positive breast cancer. According to Soliman, the phase 3 CLEOPATRA study (NCT00567190) evaluated the efficacy and safety of pertuzumab (Perjeta), trastuzumab (Herceptin), …

Cell-based method can predict how breast cancer patients will respond to treatments

In Uncategorized by Barbara Jacoby

Source: Karolinska Institutet From: news-medical.net Researchers at Karolinska Institutet in Sweden have developed a method that should be able to predict whether a patient with breast cancer will benefit from a particular treatment or not. The cell-based method has been tested on patients with promising results, according to a study published in PNAS. Several different drugs are currently available for …

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Breast cancer studies pinpoint potential new drug targets to fight resistance

In In The News by Barbara Jacoby

By Angus Liu From: fiercebiotech.com Several types of treatments are used against breast cancer, including chemotherapy, immunotherapy and drugs that target specific genes and proteins. But not all patients respond to them, so new options for reducing treatment resistance are in high demand. Now, two research groups from Italy and the University of California, San Francisco (UCSF) have identified different mechanisms in breast …

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Cardiovascular disease and mortality risk in women with breast cancer

In In The News by Barbara Jacoby

By: Coco Davis From: fredhutch.org Thanks to advances in breast cancer treatments, there are more than 3.8 million survivors of female breast cancer.  Women with invasive breast cancer have a 5-year survival rate of 90%. Although there are decreased rates of breast cancer-specific mortality, there has been an increase in cardiovascular and cerebrovascular disease-specific mortality in women with a history …

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Understanding the Difference Between Invasive and Metastatic Breast Cancer

In In The News by Barbara Jacoby

From: healthline.com Understanding Abnormal Cells Abnormal cells aren’t cancerous, but they may increase your risk of developing cancer. When you have atypical cells that haven’t spread, the cells are considered noninvasive. This is sometimes referred to as pre-cancer or stage 0 cancer. Ductal carcinoma in situ (DCIS) is an example of this. DCIS is a noninvasive breast cancer of the …

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How breast cancer treatments can affect the immune system

In In The News by Barbara Jacoby

By: Metro Creative Services From: crescent-news.com Treatment for breast cancer is highly effective. Five-year survival rates for breast cancer have increased dramatically in recent decades, and much of that success can be credited to cancer researchers and campaigns designed to inform women about the importance of screenings. Breast cancer is highly treatable, but treatment typically leads to some unwanted side …