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New compounds offer a two-for-one punch to fight estrogen-sensitive breast cancer

In Clinical Studies News by Barbara Jacoby

Source: Scripps Research Institute From: news-medical.net A set of compounds developed by scientists at Scripps Research in Florida target estrogen-sensitive breast cancer cells in new ways, potentially creating better options for patients with treatment-resistant cancers. “Hormone therapies for breast cancer have been one of the greatest success stories of molecularly targeted medicines. But a significant fraction of patients don’t respond …

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Carcinogen-exposed cells provide clues in fighting treatment-resistant cancers

In Clinical Studies News by Barbara Jacoby

Source: Massachusetts General Hospital From: eurekalert.org Researchers from Massachusetts General Hospital (MGH) have discovered a biological mechanism that transforms cells exposed to carcinogens from environmental factors like smoking and ultraviolet light into immunogenic cells that can be harnessed therapeutically to fight treatment-resistant cancers. As reported in Science Advances, that mechanism involves spurring the release of small proteins known as chemokines …