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Addition of SDX-7320 to Palbociclib Inhibits Tumor Growth in Breast Cancer Xenografts

In Clinical Studies News by Barbara Jacoby

By: Hayley Virgil From: onclive.com The addition of SDX-7320, a novel inhibitor of methionine aminopeptidase 2 (MetAP2), to palbociclib (Ibrance) was found to inhibit MCF-7 tumor growth and reduce the expression of proteins associated with resistance to palbociclib, according to data from a study virtually presented during the AACR Annual Meeting 2021.1 Results indicated that SDX-7320 and palbociclib, when given …