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Comprehensive atlas of normal breast cells offers new tool for understanding breast cancer origin

In In The News by Barbara Jacoby

By: Candace Gwaltney, Indiana University School of Medicine From: medicalxpress.com Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date. These findings offer an important tool for researchers at IU and beyond to understand how breast cancer develops and the differences in breast tissue among genetic …

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Regulatory RNAs promote breast cancer metastasis

In In The News by Barbara Jacoby

Source: Cold Spring Harbor Laboratory From: prnewswire.com Cold Spring Harbor Laboratory (CSHL) scientists have discovered a gene-regulating snippet of RNA that may contribute to the spread of many breast cancers. In animal experiments, the researchers could reduce the growth of metastatic tumors with a molecule designed to target that RNA and trigger its destruction. The same strategy, they say, could …

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Lung cancer tumor growth halved with new approach

In In The News by Barbara Jacoby

By: Maria Cohut From: medicalnewstoday.com New research from Sweden has taken strides toward finding a cure for lung cancer. It focused on noncoding molecules that have been puzzling scientists for a long time. According to the National Cancer Institute (NCI), lung cancer caused around 25.9 percent of all cancer-related deaths last year and accounted for 13.2 percent of all new …

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Blood cancer treatment ages immune cells by 30 years, study says

In In The News by Barbara Jacoby

By: Stephen Feller From: upi.com Stem cell transplants are a key treatment for blood cancers, but researchers found that for some patients it may age their immune cells by as much as 30 years. Researchers at the University of North Carolina found blood cancer patients treated with an autologous stem cell transplant showed elevated levels of expression of messenger RNA …

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Hedgehog signaling pathway for breast cancer identified

In In The News by Barbara Jacoby

From: http://medicalxpress.com Molecules called long non-coding RNAs (lncRNAs) have been implicated in breast cancer but exactly why they cause metastasis and tumor growth has been little understood…until now. Scientists at The University of Texas MD Anderson Cancer Center report that hedgehog, a unique cell signaling pathway known to contribute to many types of cancer, may be behind breast cancer metastasis. …

Findings point to an “off switch” for drug resistance in cancer

In In The News by Barbara Jacoby

Salk research points to a potential mechanism for cancer cells’ adaptability Like a colony of bacteria or species of animals, cancer cells within a tumor must evolve to survive. A dose of chemotherapy may kill hundreds of thousands of cancer cells, for example, but a single cell with a unique mutation can survive and quickly generate a new batch of …