By: Mike Bassett From: medpagetoday.com The long-term risk of distant recurrence for women with early breast cancer has declined significantly, a decades-long analysis of clinical trial data showed, largely a result of patients enrolling with lower-risk disease along with improved adjuvant therapy. In women with estrogen receptor (ER)-positive disease scheduled for at least 5 years of endocrine therapy, the 10-year …
Hormonal Contraception Linked to Increased Breast Cancer Risk in BRCA1 Carriers
By: Charles Bankhead, Senior Editor From: medpagetoday.com Carriers of the BRCA1 cancer gene had a significantly increased risk of breast cancer if they used hormonal contraception (HC), pooled cohort data showed. Breast cancer risk increased by 29% in BRCA1 carriers who reported any use of HC during at least one 12-month continuous period. The risk also increased with duration of …
Hormone Therapy for Breast Cancer Linked with Lower Dementia Risk
From: upmc.com Hormone modulating therapy (HMT) used for the treatment of breast cancer was associated with a 7% lower risk of developing Alzheimer’s disease and related dementias later in life, according to a new study published today in JAMA Network Open. The study, which is one of the largest of its kind, found that although HMT was linked with protection …
New tool predicts nerve damage risk from breast cancer treatment
Source: Linköping University Sweden From: news-medical.net Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at Linköping University in Sweden have developed a tool that can predict the risk level for each individual. The tool could help doctors adapt treatment to avoid persistent side effects in those …
Adiposity in childhood affects the risk of breast cancer by changing breast tissue composition, study suggests
By: University of Bristol From: medicalxpress.com Breast cancer is the most common cancer in women worldwide. With rates continuing to rise, there is an urgent need to identify new modifiable breast cancer risk factors. New research led by the University of Bristol suggests that higher adiposity in childhood leads to less dense breast tissue forming, which results in a reduced …
Assessing breast cancer risk
By: Mayo Clinic Staff From: newsnetwork.mayoclinic.org The genetic risk of breast cancer has been in the news lately. Researchers at the Mayo Clinic Comprehensive Cancer Center are working toward pinpointing individuals’ risk of developing breast cancer. The discovery of the BRCA1 and BRCA2 genes in the 1990s enabled many women to learn they are at high risk of developing breast …
Radiation treatment for breast cancer linked to high risk of developing subsequent skin cancer
By: Chad Van Alstin From: healthimaging.com Women who have their breast cancer treated with radiation therapy are significantly more likely to develop skin cancer in the future, a recent study shows. The findings are published in JAMA Network Open. [1] Researchers from the Stanford School of Medicine tested the hypothesis that radiation treatment for breast cancer would increase the likelihood of …
Are Food Emulsifiers Associated With Increased Cancer Risk?
By: Dr Roseline Peluchon From: medscape.com Food emulsifiers are among the most widespread food additives. A large cohort study highlighted an association between the consumption of certain emulsifiers and an increased risk for certain cancers, particularly breast and prostate cancer. Ultraprocessed foods constitute a significant part of our diet, representing approximately 30% of energy intake in France. Large epidemiologic studies …
Neoadjuvant chemotherapy may help some breast cancer patients skip regional nodal irradiation
By: American Association for Cancer Research From: medicalxpress.com For patients whose breast cancer converted from lymph node-positive to lymph node-negative disease after neoadjuvant chemotherapy, skipping adjuvant regional nodal irradiation (RNI) did not increase the risk of disease recurrence or death five years after surgery, according to results from the NRG Oncology/NSABP B-51/RTOG 1304 clinical trial presented at the San Antonio …
Benign breast disease linked to increased breast cancer risk
By: Erin T. Welsh, MA From: healio.com Key takeaways: Women with benign breast disease had higher breast cancer risks than their peers. Greater risks were seen for invasive and ductal carcinoma breast cancers. Women with benign breast disease diagnosed by percutaneous biopsies had an increased overall breast cancer risk compared with the general population, according to cohort study results published …