By: Elana Gotkine From: healthday.com For young breast cancer patients after complete excision, high- versus low-dose radiation yields slightly better local control but increased incidence of marked or moderate fibrosis in the boost area, according to a study presented at the annual European Breast Cancer Conference, held from March 20 to 22 in Milan. Sophie Bosma, M.D., Ph.D., from The …
Neoadjuvant Pembro Plus Chemo Shows EFS Benefit at 5-Years in TNBC
By: Jordyn SavaKEYNOTE-522 From: targetedonc.com The addition of neoadjuvant pembrolizumab (Keytruda) to chemotherapy, followed by adjuvant pembrolizumab reduced the risk for recurrence, progression, complications, or death vs neoadjuvant chemotherapy alone in the KEYNOTE-522 study (NCT03036488) evaluating the combination in high-risk triple-negative breast cancer (TNBC).1 According to updated findings presented at the European Society for Medical Oncology (ESMO) 2023 Annual Congress, …
Recurrence in Early-Stage Breast Cancer” Featured in Clinical Breast Cancer
Source: PreciseDx From: prnewswire.com PreciseBreast™ assessment demonstrates ability to predict the recurrence of early-stage breast cancer within 6 years PreciseDx®, a leading innovator in oncology diagnostics, leveraging Artificial Intelligence (AI) for revolutionary, morphology-driven, disease analysis, today announced that its analytical validation study for its PreciseBreast™ assessment has been published in the November 3, 2023 issue of Clinical Breast Cancer. As …
RNI Omission Yields Low Locoregional Recurrence in HR+, HER2– Breast Cancer
By: Russ Conroy From: cancernetwork.com Locoregional recurrence (LRR) rates appeared to be low among patients with hormone receptor (HR)–positive, ERBB2-negative breast cancer who did not receive regional node irradiation (RNI), according to findings from a secondary analysis of the SWOG S1007 trial. After a median follow-up of 6.1 years, the cumulative incidence of LRR was 0.85% in patients who underwent …
Study finds no link between alcohol use and breast cancer recurrence or death
Source: Kaiser Permanente From: news-medical.net A Kaiser Permanente study provides new information that may help oncologists answer one of the most common questions they hear from breast cancer survivors: Is it safe to drink alcohol? The new study, published August 9 in Cancer, is the largest prospective study to look at short-term alcohol use after breast cancer. The findings suggest …
Treatment in HR+ Early Breast Cancer May be Best Guided by Risk of Recurrence
By: Caroline Seymour From: onclive.com After settling the debate of which patients with early-stage, hormone receptor–positive breast cancer require chemotherapy in addition to endocrine therapy, investigators have set their sights on determining whether ovarian function suppression can deliver the same effects of chemotherapy and when to recommend abemaciclib (Verzenio) and olaparib (Lynparza). In the footnotes of the National Comprehensive Cancer …
Preoperative breast MRI linked to reduced recurrence risk
By: Amerigo Allegretto From: auntminnie.com Preoperative MRI is tied to reduced risk of breast cancer recurrence in patients aged 50 years or younger with cancer diagnosis and for hormone receptor-negative cancers, research presented December 1 at the RSNA annual meeting found. In her talk, Dr. Heera Yoen from Seoul National University Hospital in South Korea presented her team’s findings, which suggest …
Researchers modulate the activity of potential therapeutic target for triple-negative breast cancer
Source: University of Illinois at Urbana-Champaign From: news-medical.net Less than 20% of diagnosed breast cancers are designated “triple-negative,” lacking three types of receptors often found in other breast cancer types. But TNBCs have a higher risk of recurrence, metastasis and mortality. In a study conducted in TNBC cells and in a mouse model of the disease, researchers found that targeting …
MicroRNA can be used as a biomarker to predict breast cancer recurrence and mortality, study says
Source: American College of Surgeons From: news-medical.net MicroRNA (miRNA) can be used as a biomarker to predict which patients are likely to face breast cancer recurrence and mortality, according to study results published online ahead of print in the Journal of the American College of Surgeons (JACS). While long-term outcomes have improved for patients with breast cancer, the most common …
Breast Cancer and Vitamin D: Is there a Connection?
From: blackdoctor.org The relationship between vitamin D levels and breast cancer has generated some debate. According to recent studies, having low vitamin D levels may increase the chance of cancer recurrence. Vitamin D has extra advantages for those attempting to reduce their chance of developing breast cancer and those undergoing cancer treatment. Vitamin D: What Is It? The “sunshine vitamin” is also …