By: NRG Oncology From: medicalxpress.com The NRG Oncology (NRG)/NSABP B-39/RTOG 0413 clinical trial compared whole-breast irradiation (WBI) to accelerated partial-breast irradiation (APBI) and determined that APBI was not statistically equivalent to WBI in local tumor control. The secondary outcome for the trial was Quality-of-life (QOL). The research is published in the JNCI: Journal of the National Cancer Institute. The study …
Residing in poverty tied to worse breast cancer outcomes
By: Lori Solomon From: medicalxpress.com Women residing in persistently impoverished neighborhoods have worse breast cancer outcomes, according to a study published online Aug. 29 in JAMA Network Open. J.C. Chen, M.D., from The Ohio State University Wexner Medical Center and James Cancer Hospital in Columbus, and colleagues examined persistent neighborhood poverty and breast tumor characteristics, surgical treatment, and mortality. The …
Measuring tumor infiltrating lymphocytes predicts long term outcomes for type of early breast cancer
By: Queen Mary, University of London From: medicalxpress.com Researchers from Queen Mary University London and Emory University used a novel AI-based analytic tool to better understand how tumor infiltrating lymphocytes (TILs) can predict which cases of Ductal Carcinoma in Situ (DCIS) would go on to become invasive breast cancer. DCIS is a form of early breast cancer, where some cells …
Researchers explore gut bacteria’s role in fighting breast cancer
Source: Breast Cancer Now From: news-medical.net Researchers are investigating the function of gut bacteria in breast cancer, and how we could use it to fight against the disease, thanks to new funding from Breast Cancer Now. Bacteria living in our gut can affect our immune system and previous research in other cancers has shown a connection between healthier gut bacteria …
Study Reveals Worse Clinical Outcomes in Breast Cancer Patients Who Reported Higher Pain and Stress
By: Roswell Park Comprehensive Cancer Center From: newswise.com More studies needed to determine if reducing pain & stress could improve survival Investigators looked for links between inflammation-related factors & outcomes Phase 3 clinical trial enrolled more than 3,000 patients Secondary analyses of a phase 3 clinical trial have revealed that breast cancer patients who reported high levels of pain and stress …
Pembrolizumab May Improve Breast Cancer Outcomes Regardless of Age or Menopausal Status
From: ascopost.com The addition of the immunotherapy drug pembrolizumab to chemotherapy prior to and following surgery may lead to improved outcomes in patients with breast cancer regardless of their age or menopausal status, according to new findings presented by Cardoso et al at the 2024 European Breast Cancer Conference (EBCC) (Abstract 4). The research adds to data on the effect …
Mortgage discrimination tied to breast cancer outcomes
By: Amerigo Allegretto From: auntminnie.com Mortgage discrimination is tied to breast cancer outcomes, a study published February 20 in JAMA Network Open found. Researchers led by Jasmine Miller-Kleinhenz, PhD, from Emory University in Atlanta found that living in a historically redlined area is tied to increased odds of estrogen receptor (ER)-negative breast cancer in non-Hispanic Black women and increased odds …
Is breast cancer more common on the left side?
By: Cynthia DeMarco From: mdanderson.org A study published in Nature last fall suggests that breast cancer is slightly more common on the left side of the body than it is on the right. That same study also indicates that left-sided breast cancer is more aggressive and associated with poorer treatment outcomes. But what does that mean for people with breast …
New research finds most women diagnosed with early breast cancer can expect to become long-term survivors
By Pooja Toshniwal Paharia From: news-medical.net In a recent study published in the BMJ, researchers reported longitudinal outcomes among British women suffering from early invasive-type breast tumors as their initial tumor and those initially treated by surgical methods such as conservative surgery or mastectomy. Background Breast cancer prognosis estimates based on characteristics such as the tumor size, participant age, lymph …
Prognosis and Outcomes for Endocrine Resistant Versus Endocrine Sensitive Patients with Metastatic Breast Cancer
Source: AstraZeneca From: news-medical.net Breast cancer remains the leading cause of death for women in South America, the Middle East, and most of Europe1. 90% of breast cancer deaths are caused by metastatic disease, in which the cancer spreads to other parts of the body or recurs at a distant site. Between 20 and 30% of patients diagnosed with primary …