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Honeybee Venom Kills Aggressive Breast Cancer Cells, Boosts Chemo Agents

In In The News by Barbara Jacoby

By: Michelle Taylor From: laboratoryequipment.com In 1950, Laszlo Havas published a study in Nature that showed bee venom reduced the growth of tumors in plants. Since then, the European honeybee (Apis mellifera) has been the source of a number of medicinal products used by humans, but the molecular underpinnings of bee venom are still poorly understood. Ciara Duffy’s latest research …

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Oncogeriatric Approach Linked to More Treatment, Improved Outcomes

In Clinical Studies News by Barbara Jacoby

By: Christina Bennett, MS From: cancertherapyadvisor.com Older patients with early-stage breast cancer who were treated using an oncogeriatric approach were more likely to receive adjuvant treatments and had improved clinical outcomes compared with patients who were treated with the standard of care, found a retrospective observational study published in Breast Cancer Research and Treatment. The study included patients 70 years …

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AI can enhance accuracy of breast cancer screening, study finds

In Clinical Studies News by Barbara Jacoby

By: Brian P. Dunleavy From: upi.com Artificial intelligence-assisted mammogram screening is more accurate at identifying women with breast cancer than assessment by a radiologist, a study published Thursday by JAMA Oncology found. However, the most effective diagnostic approach combined computer algorithms with an evaluation by a radiologist, which correctly identified women with the disease 85% of the time, the researchers …

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Potential Precision Therapy for Triple-Negative Breast Cancer Found

In Clinical Studies News by Barbara Jacoby

From: clinicalomics.com In a new study of triple-negative breast cancer, scientists from the Princess Margaret Cancer Centre in Toronto and led by senior scientists Cheryl Arrowsmith, Ph.D., and Mathieu Lupien, Ph.D., reported they have found a promising approach with a protein biomarker that may potentially identify patients for more precise targeted therapy. Their findings, “GLUT1 inhibition blocks growth of RB1-positive …

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New Study Suggests Role for Hormone Therapy to Treat Even Small, T1a Breast Cancers

In In The News by Barbara Jacoby

By: Roswell Park Comprehensive Cancer Center From: newswise.com Patients with tumors under 0.5 cm have not been widely offered this treatment previously Largest known study on hormone therapy for patients with small breast tumors Analysis reveals survival benefit for patients who had endocrine therapy Hormone therapy should be discussed with these patients as treatment option Many people diagnosed with breast …

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Nearly half of breast cancer survivors experienced treatment delays due to COVID-19

In In The News by Barbara Jacoby

By: John Anderer From: studyfinds.org Over the course of this pandemic many have feared that countless Americans aren’t receiving the medical attention they need. Now, an unsettling new study seemingly confirms those concerns, at least regarding breast cancer. Researchers from the University of Illinois Chicago say that nearly half of surveyed U.S. breast cancer survivors had to deal with delays …

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Key molecule responsible for poor prognosis of breast cancer identified

In Clinical Studies News by Barbara Jacoby

Source: Hokkaido University From: eurekalert.org Hokkaido University scientists have shown that Interleukin-34 is a prognostic marker and drug target for Triple Negative Breast Cancer. Breast cancer is the most common cancer among women across the world, affecting 28.9% . Depending on the combination of cell receptor molecules present on the surface of the cancer cells, breast cancer is classified into …

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Survival Consistent for Women With Early-Stage Breast Cancer Despite Surgery Delays

In In The News by Barbara Jacoby

By: Maggie L. Shaw From: ajmc.com Delays in surgery to treat early-stage breast cancer and receiving neoadjuvant endocrine therapy did not decrease survival odds among female patients, authors report in the Journal of the American College of Surgeons. Overall delays in surgical procedures to treat early-stage breast cancer, particularly estrogen-sensitive early-stage disease, as well as receiving neoadjuvant endocrine therapy (NET) …

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Four-stranded DNA structures found to play role in breast cancer

In Clinical Studies News by Barbara Jacoby

Source: University of Cambridge From: eurekalert.org Four stranded DNA structures – known as G-quadruplexes – have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the University of Cambridge. In 1953, Cambridge researchers Francis Crick and James Watson co-authored a study published …

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Study Suggests 86-SNV Be Incorporated in Breast Cancer Risk Predication Models

In Clinical Studies News by Barbara Jacoby

By: Hannah Slater From: cancernetwork.com Researchers specifically suggested that the 86-SNV score could be incorporated into breast cancer risk prediction models for patients carrying a pathogenic variant in BRCA1, BRCA2, and CHEK2. Stratification of breast cancer risk by an 86-single nucleotide variation (SNV; formerly single-nucleotide polymorphisms) polygenic risk score (PRS) in pathogenic variant carriers of moderate-risk breast cancer genes was …