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CDH1 Linked With New Hereditary Breast Cancer Syndrome

In In The News by Barbara Jacoby

By: Cristina Ferrario From: BRCA is no longer the only gene that identifies hereditary breast cancer (BC) syndromes. Pathogenic variants of CDH1 identify a form of hereditary lobular BC (HLBC) that is unrelated to the better-known breast-ovarian syndrome linked to alterations in BRCA1 and BRCA2, according to a recent all-Italian study published in JAMA Network Open. “Pathogenic or likely pathogenic …