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Gold nanoparticle delivery of microRNA impairs metastasis in triple-negative breast cancer

In In The News by Barbara Jacoby

By: Weill Cornell Medical College From: medicalxpress.com Weill Cornell Medicine researchers have shown that giving mice with triple-negative breast cancer therapeutic microRNA (miRNA) in a protective gold nanoparticle results in significantly less spreading of cancer to the lung. Triple-negative breast cancer is a highly aggressive, difficult-to-treat form of the disease, with a high rate of metastatic recurrence. miR-708 is a …

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Gold-plated nanoparticles may reveal cancer with a finger prick blood test

In In The News by Barbara Jacoby

By: Nick Lavars From: newatlas.com Suppressed activity of small molecules called microRNA has been linked to the onset of blood-borne cancers. This is because they target other RNA molecules and stop them coding for certain proteins, with their impairment previously been linked to the formation of tumors and metastasis. Scientists in Australia have now made a breakthrough they say will …

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MicroRNA helps cancer evade immune system

In In The News by Barbara Jacoby

Salk researchers discover how oxygen-deprived tumors survive body’s immune response The immune system automatically destroys dysfunctional cells such as cancer cells, but cancerous tumors often survive nonetheless. A new study by Salk scientists shows one method by which fast-growing tumors evade anti-tumor immunity. The Salk team uncovered two gene-regulating molecules that alter cell signaling within tumor cells to survive and …

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Tel Aviv University Research Reveals How Melanoma Spreads to Other Organs in the Body

In In The News by Barbara Jacoby

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. According to a paper published today in the journal Nature Cell Biology, the scientists discovered that before spreading to other organs, a melanoma tumor sends out tiny vesicles containing molecules of microRNA. These induce morphological changes in …