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Study: Protein helps prevent breast cancer metastasis

In In The News by Barbara Jacoby

By: Tim Tedeschi, University of Cincinnati From: medicalxpress.com While better screening and improved treatments are leading to better outcomes for patients with breast cancer, 90% of breast cancer deaths are a result of metastasis, or the cancer growing and spreading to other parts of the body. University of Cincinnati Cancer Center researchers in the lab of Jun-Lin Guan, Ph.D., have …

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Rice scientists identify promising new immunological pathway to treat breast cancer bone metastases

In In The News by Barbara Jacoby

Source: Rice University From: news-medical.net Rice University researchers in the lab of chemist Han Xiao have identified a promising new immunological pathway to treat stubborn bone tumors, one of most prevalent forms of metastases in breast cancer patients. “More than 70% of people with metastatic breast cancer will see the cancer cells move to bone, which can lead to skeletal-related …

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Needle Biopsy Triggers Pro-Metastatic Changes in Breast Cancer Tumors

In In The News by Barbara Jacoby

From: insideprecisionmedicine.com Needle biopsy is indispensable to the diagnosis, typing, and targeted treatment of breast cancer. A new study, however, indicates that the testing itself triggers a series of cell-level changes that promote the spread of the disease months later. The results are the first of their kind to suggest a mechanism for the observed increases in mortality in women …

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Researchers uncover on/off switch for breast cancer metastasis

In In The News by Barbara Jacoby

By: Rebecca McClellan, Stanford University From: medicalxpress.com Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers. And many of those patients who do respond still experience metastases eventually. New research from Stanford University and the Arc Institute has revealed a better way to predict and improve patient responses. A …

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Moffitt Researchers Identify Pathway that Controls Breast Cancer Metastasis to the Brain

In In The News by Barbara Jacoby

From: moffitt.org Breast cancer is the second most common cause of brain metastasis, which occurs in 10% to 30% of patients with metastatic breast cancer. Breast cancer patients who develop brain metastasis have limited treatment options and poor survival. Moffitt Cancer Center researchers are working to better understand the molecular mechanisms that promote the development and progression of breast cancer …

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Mechanics of breast cancer metastasis discovered, offering target for treatment

In In The News by Barbara Jacoby

From: psu.edu The most lethal feature of any cancer is metastasis, the spread of cancer cells throughout the body. New research led by Penn State reveals for the first time the mechanics behind how breast cancer cells may invade healthy tissues. The discovery, showing that a motor protein called dynein powers the movement of cancer cells in soft tissue models, …

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Targeting Breast Cancer Metastasis

In In The News by Barbara Jacoby

From: the-scientist.com Breast cancer is the most frequently diagnosed cancer and contributes to 15 percent of all cancer-related deaths in women worldwide. Though 20–30 percent of patients with early-stage breast cancers eventually develop metastatic cancer, few effective treatments for preventing rapid metastatic progression exist.1 Tumor cell motility and invasion are essential drivers of metastasis, as tumor cells must migrate away …

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Newly identified stem cells can lure breast cancer to the spine

In In The News by Barbara Jacoby

By: Meghan Rosen From: sciencenews.org When breast cancer spreads, it often targets the spine. Now scientists may have finally discovered why. A newfound kind of stem cell drives cancer cells to bones in the vertebrae, pathologist Matthew Greenblatt of Weill Cornell Medicine in New York City and his colleagues report September 13 in Nature. The find helps explain a long-standing …

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Rice, Baylor developing ‘glyco-immune’ checkpoint inhibitor

In In The News by Barbara Jacoby

From: prnewswire.com Defense Department backs development of immunotherapy for breast cancer bone metastasis Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind “glyco-immune” checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors. Breast cancer often migrates to other organs. As many as 40% of breast cancer survivors are diagnosed with …

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Could a Cardiac Drug Stop Breast Cancer Metastasis?

In In The News by Barbara Jacoby

By: Kara Baskin From: tufts.edu Triple-negative breast cancer is notoriously hard to treat. Assistant Professor Madeleine Oudin’s lab at the School of Engineering studies how to tame those cancer cells into submission. With Laidlaw Scholar Deepti Srinivasan, a senior biomedical engineering major and an aspiring physician, Oudin investigated how manipulating potassium channel activity could alter those cells’ bioelectric signals—making the cancer …