From: healthline.com Breast cancer can spread through your lymph circulatory system to your lymph nodes. In later stages, it can also spread to other organs, like your brain or lungs. When breast cancer spreads to other sites in the body, doctors call this “metastasizing.” There are several ways cancer can spread in the body. Breast cancer can spread lymphatically from …
Clinical study confirms tissue stiffening in breast cancer can drive metastasis
By: Mark Febbo, University of Arizona Cancer Center From: healthsciences.arizona.edu A study published in Clinical Cancer Research confirmed that tissue stiffening in the most common types of breast cancer, HER2-negative, can directly cause disease progression and metastasis, leading to detrimental outcomes for patients. The work was a collaboration between researchers at the University of Arizona Health Sciences and clinicians in Spain. Researchers …
RK-33 May Be Significant in Treatment of Breast Cancer Bone Metastasis
By: Gillian McGovern From: pharmacytimes.com Key Takeaways RK-33 targets DDX3, an RNA helicase elevated in cancer cells, to inhibit breast cancer bone metastasis. In mouse models, RK-33 eliminated bone metastases and prevented further cancer spread without significant adverse effects. A study published in Cancer Letters demonstrated new promise in the treatment of breast cancer bone metastasis, or breast cancer that …
In vitro model helps show why breast cancer spreads to bone
By: Tampere University From: medicalxpress.com Researchers from Tampere University, Finland, and Izmir Institute of Technology, Turkey, have developed an in vitro cancer model to investigate why breast cancer spreads to bone. Their findings hold promise for advancing the development of preclinical tools to predict breast cancer bone metastasis. Breast cancer is a significant global public health challenge, with 2.3 million …
Bria-IMT Plus Immunotherapy Shows Early Promise in Breast Cancer Brain Metastasis
By: Ashling Wahner From: onclive.com The targeted cell-based immunotherapy Bria-IMT (SV-BR-1-GM) in combination with an immune checkpoint inhibitor elicited an antitumor response, including the complete resolution of a breast cancer metastasis in the right temporal lobe region of the brain, in a patient treated in a phase 1/2 trial (NCT03328026).1 The patient’s temporal lobe tumor was no longer detectable via …
Researchers Uncover Key Actor in Spread of Breast Cancer to the Brain
By: Rob Levy From: dana-farber.org Dana-Farber researchers have identified a key mechanism involving the KMT2C and KMT2D genes that drives breast cancer metastasis to the brain. The study highlights the role of the KDM6A protein in promoting this spread, particularly in patients with triple-negative breast cancer. This discovery opens the door to potential new treatments targeting KDM6A to prevent brain …
Drug shows promise for treating brain tumors resulting from breast cancer, trial reports
By: Steven Lee, University of Texas Health Science Center at San Antonio Fr0m: medicalxpress.com A drug effective in treating breast cancer shows new promise in addressing breast cancer with brain metastases or recurrent glioblastoma, as reported by results of a prospective window-of-opportunity trial at the University of Texas Health Science Center at San Antonio (UT Health San Antonio). The window …
New biological mechanism uncovered for treating breast cancer metastasis to the brain
Source: University of Arizona From: news-medical.net A study led by researchers from the University of Arizona Cancer Center at UArizona Health Sciences identified a biological mechanism that could lead to more effective treatments for breast cancer that has metastasized to the brain. By studying the metabolic differences between primary breast cancer cells and those that metastasize to the brain, they determined that …
New AI tool to detect possible metastatic breast cancer
From: utsouthwestern.edu Researchers at UT Southwestern Medical Center have developed a novel artificial intelligence (AI) model to improve the detection of breast cancer metastasis, which could reduce the need for needle or surgical biopsies. The noninvasive model uses standard magnetic resonance imaging (MRI), paired with machine learning AI, to detect axillary metastasis – the presence of cancer cells in the …
How Does Breast Cancer Spread or Metastasize?
Breast cancer can spread through your lymph circulatory system to your lymph nodes. In later stages, it can also spread to other organs, like your brain or lungs. When breast cancer spreads to other sites in the body, doctors call this “metastasizing.” There are several ways cancer can spread in the body. Breast cancer can spread lymphatically from the breast …