From: cornell.edu Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical …
Diamond-based sensor advances detection of metastasized breast cancer
Source: University of Warwick From: news-medical.net University of Warwick researchers have built a new diamond-based magnetic field sensor that could be used to better find tumors through tracing magnetic fluid injected in the body. A cancer diagnosis is most problematic when cells from the tumor have metastasized (spread) to other organs. This most often occurs through the lymph nodes and …
Mitochondrial antioxidant found to drive breast cancer metastasis
By: Kivanç Birsoy, Ph.D. From: rockefeller.edu The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer. Now, new evidence points to the mitochondrial metabolite glutathione, highlighting its central role in helping breast cancer cells break away from the primary tumor, travel through the body, and take root in …
Breast Cancer Cells Steal Mitochondria from Neurons to Fuel Metastasis
By: Andrea Lius, PhD From: the-scientist.com o survive in ever-changing conditions in the body, cancer cells often need to alter their metabolism.1 This ability to adapt is especially critical for their spread to other parts of the body. As “powerhouses of the cell,” mitochondria have been linked to metabolic reprogramming and disease progression in various types of cancer.2 Over the …
How Triple-Negative Breast Cancer Cells Metastasize
By: Greg Glasgow From: cuanschutz.edu Newly published research led by Heide Ford, PhD, associate director of basic research at the University of Colorado Cancer Center, sheds new light on how triple-negative breast cancer cells evade immune surveillance to spread to other sites in the body. In a paper that came out in May in the journal Science Advances, Ford and her co-investigators show that a family …
What New Interventional Radiology Research Reveals About Treatment for Breast Cancer Liver Metastases
By: Jeff Hall From: diagnosticimaging.com Emerging research from the recent Society of Interventional Radiology (SIR) conference suggests the combination of transarterial radioembolization (TARE) and immunotherapy may offer improved three-year survival outcomes for patients with breast cancer and liver metastases. For patients with breast cancer liver metastases, the combination of immunotherapy and transarterial radioembolization (TARE) may significantly enhance survival outcomes over …
Breast Cancer Metastasis: Common Sites, Symptoms, and More
From: healthline.com When breast cancer spreads to other areas, it’s called metastatic, or stage 4, breast cancer. Breast cancer can spread to your bones, lungs, liver, and brain, among other parts of your body. According to the National Cancer InstituteTrusted Source, the most common metastasis locations for breast cancer are the: bones lungs liver brain In a 2020 studyTrusted Source …
How Does Breast Cancer Spread or Metastasize?
From: healthline.com Breast cancer can spread through your lymph circulatory system to your lymph nodes. In later stages, it can also spread to other organs, like your brain or lungs. When breast cancer spreads to other sites in the body, doctors call this “metastasizing.” There are several ways cancer can spread in the body. Breast cancer can spread lymphatically from …
Clinical study confirms tissue stiffening in breast cancer can drive metastasis
By: Mark Febbo, University of Arizona Cancer Center From: healthsciences.arizona.edu A study published in Clinical Cancer Research confirmed that tissue stiffening in the most common types of breast cancer, HER2-negative, can directly cause disease progression and metastasis, leading to detrimental outcomes for patients. The work was a collaboration between researchers at the University of Arizona Health Sciences and clinicians in Spain. Researchers …
RK-33 May Be Significant in Treatment of Breast Cancer Bone Metastasis
By: Gillian McGovern From: pharmacytimes.com Key Takeaways RK-33 targets DDX3, an RNA helicase elevated in cancer cells, to inhibit breast cancer bone metastasis. In mouse models, RK-33 eliminated bone metastases and prevented further cancer spread without significant adverse effects. A study published in Cancer Letters demonstrated new promise in the treatment of breast cancer bone metastasis, or breast cancer that …