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Triple-negative breast cancer metastases in lungs contain more diverse cells than those in liver

In In The News by Barbara Jacoby

Source: American Association for the Advancement of Science From: eurekalert.org The site of breast cancer metastases dictates their clonal composition and reversible transcriptomic profile Metastatic tumors originating from notoriously aggressive triple-negative breast cancer that emerge in the lungs contain a more diverse array of cancer cells than those that arise in the liver, according to a new study in mice …

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New study sheds light on cancer metastasis

In Clinical Studies News by Barbara Jacoby

Source: University of Colorado Anschutz Medical Campus From: news-medical.net Breast cancer is harmful enough on its own, but when cancer cells start to metastasize — or spread into the body from their original location — the disease becomes even more fatal and difficult to treat. Thanks to new research published in Oncogene from the lab of University of Colorado Cancer …

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A lack of oxygen in tumors promotes metastasis

In In The News by Barbara Jacoby

Source: University of Basel From: eurekalert.org Metastases are formed by cancer cells that break away from the primary tumor. A research group at the University of Basel has now identified lack of oxygen as the trigger for this process. The results reveal an important relationship between the oxygen supply to tumors and the formation of metastases. This research may open …

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Isolated perfusion therapy with chemofiltration leads to rapid remissions with maintained and improved quality of life for women with ovarian cancer

In In The News by Barbara Jacoby

Source: Medias-Klinikum Burghausen Ovarian tumours are among the most aggressive cancers in women and rank fifth in all gynaecological cancers. The disease is often only recognised very late and is then hardly controllable. Only about one third of the patients survive the five years after the initial diagnosis. If metastases have already formed in the abdomen, often only a radical …

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Metastatic Breast Cancer: What You Should Know

In In The News by Barbara Jacoby

By: Rene Wisely From: uofmhealth.org What does it mean to have metastatic, or stage 4, breast cancer? A Rogel Cancer Center oncologist explains the diagnosis and how it’s treated. After hearing a diagnosis of metastatic breast cancer, a rush of questions emerges. But often, it’s not until long after leaving the doctor’s office. Metastatic means the cancer has spread beyond …

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How one DNA mutation in breast cancer hijacks the immune system

In In The News by Barbara Jacoby

One defective gene in breast tumour cells can promote metastases elsewhere in the body by steering the immune system in an undesirable direction. This is the p53 gene, which is deleted or mutated in the tumour cells of nearly 40% of all breast cancer patients. An article about this discovery by the research group of immunologist and tumour biologist Karin …

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The power of electromagnetic energy on breast cancer cells

In In The News by Barbara Jacoby

By: Lauren Sharkey From: medicalnewstoday.com Cancer’s ability to spread throughout the body can turn a curable case into an aggressive and sometimes fatal one. A team of engineers and cancer biologists may have found a way to slow down, and even stop, the migration of breast cancer cells.  Cancer, by nature, is a destructive force. Sometimes, it spreads, or metastasizes, …

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Researchers find potent chemical agents that can thwart cancer metastasis

In In The News by Barbara Jacoby

Source: University of California – Riverside From: phys.org Recently, a research team led by Maurizio Pellecchia at the University of California, Riverside, discovered a way for chemotherapy drug paclitaxel to target migrating, or circulating, cancer cells, which are responsible for the development of tumor metastases. The team was successful in getting the drug to piggyback on 123B9, an agent they …

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Cancer spreads even before tumours form

In In The News by Barbara Jacoby

By: Sushmi Dey, TNN From: economictimes.indiatimes.com In a new discovery that might challenge the existing knowledge of cancer and methods to treat it, researchers have found cancer cells spread to organs much earlier than was thought. In fact, cancer cells can spread even before a tumour develops, remain quiet for long periods of time and then awaken to form aggressive …

Breast cancer patient finds new hope with potentially revolutionary treatment

In In The News by Barbara Jacoby

Source: City of Hope From: news-medical.net City of Hope patient Susan Young has had a remarkable response to a potentially revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding protein. The 69-year-old came to City of Hope in August 2016 from UC Davis with advanced triple-negative breast cancer that had metastasized …