By: Candace Gwaltney, Indiana University School of Medicine From: medicalxpress.com Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date. These findings offer an important tool for researchers at IU and beyond to understand how breast cancer develops and the differences in breast tissue among genetic …
IU School of Medicine scientists discover ‘game-changer’ treatment for triple negative breast cancer
From: miragenews.com A team of Indiana University School of Medicine researchers has developed a novel antibody-drug conjugate for treating triple negative breast cancer. The study, led by senior author Xiongbin Lu, Vera Bradley Foundation Professor of Breast Cancer Innovation at the IU School of Medicine, has been published in the prestigious interdisciplinary medical journal, Science Translational Medicine. Triple negative breast …
IU researchers identify how breast cancer cells evade immune attacks
Source: Indiana University School of Medicine From: news-medical.net Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients. Xinna Zhang, PhD, and colleagues found that when breast cancer cells have an increased level of a …
Blood-based Biomarkers Can Help To Predict Recurrence of Triple Negative Breast Cancer
Source: Indiana University School of Medicine From: technologynetworks.com Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women’s blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative …
Physics could answer questions about breast cancer spreading to bones
IUPUI researchers hope to learn how cancer cells generate enough force to move from a tumor site through the body and then settle into bones To fully understand why breast cancer spreads, or metastasizes, you must also consider the how. That’s what researchers in a biophysics and imaging laboratory in the School of Science at IUPUI did as they studied …
IU Precision Health Initiative has dramatic results for triple negative breast cancer patient
By: Christine Drury From: iu.edu Five years ago, Jackie Stephens rolled over in bed and felt a horrible pain in her right breast. A subsequent mammogram revealed a large lump in her right breast and two smaller ones. Her diagnosis: triple negative breast cancer. Stephens’ oncologist prescribed a treatment regimen of chemotherapy, a lumpectomy and radiation. When her treatment was …
Enzymes ‘partner up’ to accelerate cancer, aging diseases
Source: Indiana University From: sciencedaily.com Researchers have identified cellular processes that appear to supercharge both the growth and shrinkage of the chemical ‘caps’ on chromosomes associated with aging, called telomeres. A new study from molecular biologists at Indiana University has identified cellular processes that appear to supercharge both the growth and shrinkage of the chemical “caps” on chromosomes associated with …
Study Shows First Practical Intervention for Chemobrain
SAN FRANCISCO, CA (October 31, 2016) – For the first time, symptoms of cancer-related cognitive decline – often called “chemobrain” – were reversed in a large, home-based, randomized controlled trial, using unique computerized brain exercises, according to a report today in the Journal of Clinical Oncology. Breast cancer support groups first brought attention to a phenomenon they called “chemobrain” or …