From: technologynetworks.com Adding an immunotherapy drug to the chemotherapy that patients receive can dramatically improve breast cancer cure rates. A Peter Mac-led international clinical trial has shown adding an immunotherapy drug to the chemotherapy that patients receive ahead of surgery can dramatically improve breast cancer cure rates. The Phase III CheckMate-7FL trial involved 510 people with the “ER+/HER2-” sub-type which …
Cell-based immunotherapy shows promise in early clinical trial for breast cance
By: Kent State University From: medicalxpress.com A phase one clinical trial exploring a novel cell-based immunotherapy for breast cancer has been published in JAMA Oncology. The technology tested in the trial was co-developed by Gary Koski, Ph.D., professor in Kent State University’s Department of Biological Sciences, and Brian J. Czerniecki, M.D., Ph.D., chair and senior member in the Moffitt Cancer …
Benefits of Neoadjuvant Immunotherapy in Breast Cancer Extend Beyond TNBC
By: Charles Bankhead From: medpagetoday.com Neoadjuvant, but not adjuvant, chemoimmunotherapy significantly improved key outcomes in certain patients with early breast cancer, according to a meta-analysis involving more than 5,000 patients. Consistent with existing evidence, the addition of immune checkpoint inhibitors (ICIs) to neoadjuvant chemotherapy improved pathologic complete response (pCR) rates in triple-negative breast cancer (TNBC) by an absolute difference of …
Breakthrough immunotherapy targets non-cancer cells to prevent breast cancer spread
Source: Breast Cancer Now From: news-medical.net A new type of immunotherapy that targets non-cancer cells could help prevent the growth and spread of breast cancer tumors, according to new research funded by Breast Cancer Now. The discovery, published today (28 February) in The Journal for ImmunoTherapy of Cancer, has found that an immunotherapy approach targeting a protein called endosialin disrupts …
Researchers Discover Breakthrough in Immunotherapy’s Side Effects
From: breastadvocateapp.com Researchers at the University of Michigan Health Rogel Cancer Center have made a significant breakthrough in understanding and mitigating severe gastrointestinal problems associated with immune-based cancer treatment. This discovery could lead to more effective cancer therapies with fewer adverse effects. Immunotherapy’s Promise and Pitfalls Immunotherapy has gained prominence as a promising approach for treating various types of cancer. …
Combination Radiation with Immunotherapy Shows Promise Against “Cold” Breast Cancer Tumors
From: news.weill.cornell.edu Researchers at Weill Cornell Medicine have discovered that radiation therapy combined with two types of immunotherapy—one that boosts T cells, and another that boosts dendritic cells—can control tumors in preclinical models of triple negative breast cancer, a cancer type that’s typically resistant to immunotherapy alone. Immunotherapy activates the body’s own immune system to fight cancer but isn’t effective …
Revolutionary New Technology Predicts Cancer Patients’ Response to Immunotherapy
From: prnewswire.com A team of researchers from Ben-Gurion University of the Negev (BGU) has developed a groundbreaking bio-sensing technology that predicts the response of cancer patients to anti-PD1, an immune checkpoint inhibitor (ICI) therapy, with significantly greater accuracy than current methods. The study’s results were published late last week in the prestigious journal Science Advances. The study was led by Bar …
Immunotherapy to shrink treatment-resistant cancer tumors
By: Pai Liu, Michigan State University From: medicalxpress.com Advancements in cancer research and treatment have resulted in great improvements in survival rates—today, there are almost 17 million people in the United States alone who have survived their diagnosis because of the physicians and scientists who have dedicated their careers to breakthrough approaches. June is Cancer Survivor Month, and as we …
Radical increase in the effectiveness of breast cancer immunotherapy
By: IMIM (Hospital del Mar Medical Research Institute) From: medicalxpress.com A study published in the journal Nature Cancer, carried out within the Cancer Program at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan …
NIH study advances personalized immunotherapy for metastatic breast cancer
From: nih.gov An experimental form of immunotherapy that uses an individual’s own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute’s (NCI) Center for Cancer Research, part of the National Institutes of Health. Many people with metastatic breast cancer …