From: insideprecisionmedicine.com Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School, and Memorial Sloan Kettering Cancer Center (MSK) have identified early genetic alterations in healthy women’s breast cells that could be among the first steps leading to breast cancer. The findings, published today in Nature Genetics, suggest that cancer-like mutations appear silently in breast cells that …
Black and White Women Have Same Mutations Linked to Breast Cancer Risk
From: pennmedicine.org Penn study underscores importance of addressing genetic testing disparity in Black women The prevalence of genetic mutations associated with breast cancer in Black and white women is the same, according to a new JAMA Oncology study of nearly 30,000 patients led by researchers in the Basser Center for BRCA at the Abramson Cancer Center. About five percent of …
New analytical model detects mutations in breast cancer
Source: Lund University From: eurekalert.org Researchers at Lund University in Sweden have developed a computational model which is effective in detecting and identifying genetic mutations in breast tumours. The study, the largest of its kind in the world, includes results from over 3 200 patients with breast cancer. The researchers used RNA sequencing, a sensitive, precise tool which has very …
New Guidelines on Managing Hereditary Breast Cancer
By: Jamie DePolo From: breastcancer.org Three professional organizations have put out guidelines on how to treat and manage breast cancer in people with a genetic mutation linked to a higher risk of the disease. The guidelines were published online on April 3, 2020, by the Journal of Clinical Oncology. Read “Management of Hereditary Breast Cancer: American Society of Clinical Oncology, …
Genetic testing results may reduce likelihood of guideline-concordant breast cancer treatment
By: Allison W. Kurian From: healio.com Women with breast cancer who tested positive for certain genetic mutations appeared more likely to receive distinct treatments, according to results of a population-based cohort study published in JAMA Oncology. “These treatment patterns may be less concordant with practice guidelines, particularly for radiotherapy and chemotherapy,” Allison W. Kurian, MD, MSc, associate professor of medicine …
Personalized Blood Test Improves MRD Detection in Patients with Breast Cancer
By: Hannah Slater From: cancernetwork.com A study, published in Clinical Cancer Research, found that tracking large numbers of individualized tumor mutations in cell-free DNA (cfDNA) can improve minimal residual disease (MRD) detection in patients with breast cancer; however, its sensitivity is driven by the number of tumor mutations available to track.1 Given these findings, researchers predict that tracking even more mutations …
Updated Genetic Screening Guidelines Published by National Comprehensive Cancer Network Feature Emerging Evidence on Personalized Medicine
Newly updated and expanded NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic clarify who should be tested for cancer-causing genetic mutations. Experts caution about risks of direct-to-consumer genetic testing and stress the importance of genetic counseling. The National Comprehensive Cancer Network® (NCCN®) today announced publication of the newest genetic risk assessment recommendations for breast, ovarian and pancreatic cancers. …
Men with Genetic Mutations: What You Need to Know
By: Kristie L. Kahl From: curetoday.com Cancer risk and management of men with genetic mutations is not focused on nearly enough, according to Rachel Shapira, Sc.M., LCGC. “Part of the problem is it is really easy to get caught up thinking about all of the risks for women because there is a lot we have to think about … but …
Research raises hope for colon cancer prevention drug
By: Marie McCullough From: philly.com Most experts say colon cancer is a multistage disease driven by the accumulation of genetic mutations. Not Scott A. Waldman. The Thomas Jefferson University researcher has spent decades bolstering the iconoclastic idea that colon cancer is basically a hormone-deficiency disease – one that can be reversed or even prevented by restoring the hormone. Now, Waldman’s …
New therapies offer hope to cancer patients
By: Hudson Sangree From: sacbee.com Gale Kilgore, a retired medical librarian in Amador County, went to the doctor two years ago for what she suspected was a urinary tract infection. She learned she had bladder cancer. Doctors at Sutter Amador Hospital removed the tumor from her bladder, only to discover the cancer had spread to surrounding muscle. A subsequent round …
- Page 1 of 2
- 1
- 2