By Public Library of Science From: medicalxpress.com Breast cancer cells ingest and consume the matrix surrounding them to overcome starvation, according to a new study published January 16 in the open access journal PLOS Biology, by Elena Rainero of the University of Sheffield, UK, and colleagues. The finding elucidates a previously unknown mechanism of cancer cell survival, and may offer …
Breast Cancer Becomes Vulnerable to Immune Cells Through DDR1 Deactivation
From: genengnews.com Immune exclusion, or the lack of immune cells in the vicinity of cancer cells, predicts poor patient outcomes in multiple cancers, including triple-negative breast cancer (TNBC). Now, researchers have identified a key molecule, discoidin domain receptor 1 (DDR1), that prevents immune cells from entering tumors and killing the cancer cells inside through the formation of the extracellular matrix (ECM). …
Aging breast tissue could set the stage for invasive breast cancer
Source: University of Notre Dame From: sciencedaily.com The American Cancer Society estimates that 284,200 women will be newly diagnosed with breast cancer in 2021, and 43,600 will die of the disease — the second highest cause of cancer death in women. A woman’s risk of being diagnosed with breast cancer increases with age, but while scientists have long studied cellular …
TGen-led study results suggest more accurate diagnostic for breast cancer
Source: The Translational Genomics Research Institute From: eurekalert.org Breast cancer, even at its initial stages, could be detected earlier and more accurately than current techniques using blood samples and a unique proteomics-based technology, according to findings of a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. Patrick Pirrotte, Ph.D., an Assistant Professor and …