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UChicago Medicine enrolling patients in LymphBridge™ clinical study for surgical treatment of breast cancer-related lymphedema

In In The News by Barbara Jacoby

By: University of Chicago Medical Center From: newswise.com The University of Chicago Medicine has announced today that it is now enrolling patients in LymphBridge™, a randomized clinical study to evaluate a novel surgical treatment for addressing breast cancer-related lymphedema. This study is sponsored by Fibralign Corporation with funding provided by the National Cancer Institute (NCI) and being led by world-renowned …

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New drug could help in breast cancer fight, Scottish research finds

In Clinical Studies News by Barbara Jacoby

By: Craig Cairns From: thenational.scot A PROTEIN which helps breast cancer tumours survive could be targeted with a new type of drug that is already being tested for other cancers, research suggests The protein, known as MCL-1, helps breast cancer cells survive by hindering their natural ability to die. This process, called apoptosis, is the body’s way of getting rid …

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Changes detected in BRCA1 breast cells before they turn cancerous

In Clinical Studies News by Barbara Jacoby

From: cancerresearchuk.org A new study funded by Cancer Research UK has mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear, which could have significant implications for the early detection of breast cancer. The paper, published today in Nature Communications(link is external), has discovered that before becoming cancerous, breast cells with the BRCA1 …

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Medifirst Solutions Announces a Clinical Study for a Breast Cancer Diagnostic Medical Device

In Clinical Studies News by Barbara Jacoby

Source: Globe Newswire From: biospace.com MEDIFIRST SOLUTIONS, INC. (OTC: MFST) (the “Company” or “Medifirst”), is pleased to announce it is a Sponsor and Collaborator for an upcoming breast cancer clinical study for real-time margin detection. About 1 in 8 U.S. women will develop invasive breast cancer over the course of her lifetime. Besides skin cancer, breast cancer is the most commonly diagnosed …

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Estradiol Challenge Test ‘Highly Predictive’ of Response to Endocrine Therapy in Patients With ER-Positive Breast Cancer

In Clinical Studies News by Barbara Jacoby

By: Leah Lawrence From: cancertherapyadvisor.com The use of a positron emission tomography (PET)-based estradiol challenge test was found to be highly predictive of response to endocrine therapy in women with estrogen-receptor (ER)-positive breast cancer. In the phase 2 study (NCT02455453), data from which were published in Nature Communications, the investigators measured the responses to endocrine therapy by monitoring the change …

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Study Identifies Breast Cancer Risk and Disease-Causing Mutations in Women Over 65

In Clinical Studies News by Barbara Jacoby

By: Hannah Slater From: cancernetwork.com Women with onset of breast cancer over age 65 typically do not qualify for genetic testing, however this study demonstrated that frequency of pathogenic variants and risk of breast cancer is not negligible in this patient population. A study presented at the American Society of Human Genetics 2020 Virtual Meeting provided estimates of prevalence and …

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Early-Onset Breast Cancer Possibly Linked to Preeclamptic Pregnancy, High Birth Weight

In Clinical Studies News by Barbara Jacoby

By: Maggie L. Shaw From: ajmc.com With little research on the subject, the investigators sought out a connection between certain perinatal factors and risk of young-onset breast cancer in a sister-matched case-control study. Certain perinatal factors have been shown to possibly exert influence over an increased risk of developing early-onset breast cancer, reported a study published in Breast Cancer Research. …

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Nurse-Led Cognitive Behavioral Therapy Program Aids Management of Hot Flushes in Women With a History of Breast Cancer

In Clinical Studies News by Barbara Jacoby

By: Susan Moench, PhD, PA-C From: oncologynurseadvisor.com Patients with a history of breast cancer experiencing hot flushes and night sweats (HFNS) reported significant improvement in related quality-of-life measures following a nurse-led cognitive behavioral therapy (CBT) intervention compared with usual care, according to results of a randomized clinical trial published in Psycho-Oncology. Hot flushes and night sweats (HFNS) are commonly experienced …

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Dr. Anders on Abemaciclib in HR+ Breast Cancer With Brain Metastases

In Clinical Studies News by Barbara Jacoby

By: Carey Anders, MD From: onclive.com Carey Anders, MD, director, Brain and Spine Metastasis Program, Duke Cancer Institute, discussed the use of abemaciclib (Verzenio), a selective CDK4/6 inhibitor, in patients with hormone receptor–positive, HER2-negative metastatic brain cancer with brain metastases. In the study, 52 patients were evaluated and had a median of 4 prior systemic therapies. Of the group, 75% …

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Celsion Announces IRB Approval to Begin a Clinical Study of ThermoDox® Plus High Intensity Focused Ultrasound in Breast Cancer Patients at University Medical Center Utrecht in the Netherlands

In Clinical Studies News by Barbara Jacoby

Source: Celsion CORP From: globenewswire.com An Investigator-Sponsored Phase I Safety and Feasibility Study Estimated to Begin Enrollment in the Second Half of 2019 The Study Further Reinforces the Broad Potential of ThermoDox to Treat a Range of Solid Tumors with Multiple Localized Heating Sources Celsion Corporation (NASDAQ: CLSN), an oncology drug-development company, announces that the University Medical Center Utrecht in …