By: Jason Harris From: onclive.com Perou is the May Goldman Shaw Distinguished Professor of Molecular Oncology, codirector of the Computational Medicine Program, faculty director of the UNC Lineberger Bioinformatics Group, codirector of the UNC Lineberger Breast Cancer Research Program, and a professor in the department of genetics at the University of North Carolina Lineburger Comprehensive Cancer Center. He is also …
Chemo Creates Leaky Blood Vessels Helping Cancer Cells To Spread
From: technologynetworks.com A new study adds to the evidence that chemotherapy enhances cancer’s spread beyond the primary tumor, showing how one chemo drug allows breast cancer cells to squeeze through and attach to blood vessel linings in the lungs. The research in mice leaves no doubt that the chemo drug caused changes to non-cancer cells that enable this process. Scientists …
What You Need to Know About Breast Cancer Chemotherapy Pills
From: healthline.com People commonly associate chemotherapy with intravenous (IV) cancer drugs in a hospital or doctor’s office. This has been the traditional nonsurgical method of treating cancer. Due to recent advances in cancer treatments, oral chemotherapy pills have become more widely used for many types of cancer. There are a few that are approved for breast cancer, including capecitabine (Xeloda), …
Chemotherapy does not affect complication rate or patient satisfaction for breast reconstruction
By: Mary Clare Fischer From: uofmhealth.org Among those who underwent a mastectomy and breast reconstruction, there were no significant differences in complication rate or patient well-being for women who received chemotherapy as an additional treatment compared to those who did not. Receiving chemotherapy as additional treatment for breast cancer did not increase the complication rate for women who underwent a …
NCCN Releases New Patient Guidelines on Anemia and Neutropenia
New resource helps patients and caregivers recognize and understand blood cell production deficiencies, to better participate in their care planning; available for free at NCCN.org/patientguidelines The National Comprehensive Cancer Network® (NCCN®) announced today the publication of new NCCN Guidelines for Patients®: Anemia and Neutropenia, Low Red and White Blood Cell Counts funded by the NCCN Foundation® and endorsed by The …
MINDACT points to differential breast cancer chemotherapy benefit by age
By: hreeya Nanda From: medwirenews.com Exploratory data from the MINDACT trial suggest that women older than 50 years who have high clinical risk but low genomic risk according to the 70-gene MammaPrint signature may be able to forgo adjuvant chemotherapy for early-stage breast cancer. By contrast, “in younger women, a potentially clinically relevant chemotherapy benefit of about 5 percentage points is …
What Treatment Options Exist for Advanced Breast Cancer?
From: healthline.com Having an advanced form of cancer can feel like you have little or no treatment options. But that’s not the case. Find out what options are available to you and start getting on the right type of treatment. Hormone therapy There are several hormone therapies to treat advanced hormone receptor-positive (estrogen receptor-positive or progesterone receptor-positive) breast cancers: Tamoxifen …
7 Things to Know About Managing Chemotherapy Hair Loss
From: healthline.com For many people living with cancer, chemotherapy can help stop the spread of the disease. But it can also cause side effects, including hair loss. This can be a source of stress. Getting more information about chemo-related hair loss may help you feel better prepared. Here are seven facts about hair loss from chemotherapy, including strategies to manage …
Can Melatonin Alleviate Symptoms of Cognitive Impairment in Patients With Breast Cancer?
By: Maggie L. Shaw From: ajmc.com Cognitive impairment is a well-documented adverse effect (AE) of treatment from breast cancer, and it can appear soon after treatment begins or far down the road. The rate of occurrence, however, during chemotherapy is more than twice that from before treatment: 52% versus 23%, respectively. Oral melatonin may be of benefit to these patients. …
Adjuvant Chemoendocrine Therapy May Be Associated With Cognitive Impairment
By: Hannah Slater From: cancernetwork.com Results from a subgroup of the TAILORx trial, published in the Journal of Clinical Oncology, suggested that adjuvant chemoendocrine therapy is associated with significantly greater cancer-related cognitive impairment (CRCI) compared with endocrine therapy alone among women with breast cancer at 3 and 6 months.1 However, these differences receded over time, with no significant differences observed at …