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Advances in Breast Cancer

In In The News by Barbara Jacoby

From: newsinhealth.nih.gov Screening and Treatment Get Personal Researchers are studying the risk factors for different types of breast cancer. They’re also searching for more personalized treatments. Unraveling The Risks “Breast cancer is caused by a combination of factors,” says Dr. Montserrat García-Closas, a cancer researcher at NIH. Your genes, lifestyle, and environment all contribute to your risk. Researchers are trying …

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Physicians must ‘take responsibility’ for bone health of cancer survivors

In In The News by Barbara Jacoby

By: Talitha Bennett From: healio.com “Bone health is a significant issue for cancer survivorship, mostly in [patients with] prostate cancer and breast cancer because of the prevalence of those cancers,” Charles L. Shapiro, MD, FASCO, professor of hematology and medical oncology at the Icahn School of Medicine at Mount Sinai and a HemOnc Today Editorial Board Member, told Healio in …

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Study unveils many ways carcinogens trigger development of breast cancer

In In The News by Barbara Jacoby

Source: Silent Spring Institute From: eurekalert.org In the most comprehensive review to date of how breast cancer develops, scientists have created a detailed map that describes the many ways in which environmental chemicals can trigger the disease. Using ionizing radiation as a model, the researchers identified key mechanisms within cells that when disrupted cause breast cancer. Because the findings can …

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Age Associated With Benefit Derived From Chemotherapy for Women With Luminal Breast Cancer, MINDACT Trial Finds

In Clinical Studies News by Barbara Jacoby

By: Matthew Gavidia From: ajmc.com Data from the MINDACT trial revealed that among women with luminal breast cancers (hormone receptor–positive, HER2-negative by local pathology) with a high clinical risk and low genomic risk, those aged 40 to 50 years had a greater benefit from chemotherapy than patients older than 50. In a recent analysis of the TAILORx trial, patients who …

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Uncovering a new principle in chemotherapy resistance in breast cancer

In In The News by Barbara Jacoby

Source: National Institutes of Health From: nih.gov A laboratory study has revealed an entirely unexpected process for acquiring drug resistance that bypasses the need to re-establish DNA damage repair in breast cancers that have mutant BRCA1 or BRCA2 genes. The findings, reported by Andre Nussenzweig, Ph.D., and Shyam Sharan, Ph.D., at the National Cancer Institute (NCI), part of the National …

Research team discovers key mechanisms to inhibit triple negative breast cancers

In In The News by Barbara Jacoby

From: healthcanal.com Findings could lead to life-saving treatments to fight tumor metastasis A team of researchers from Cleveland Clinic and Case Western Reserve School of Medicine have identified critical complex mechanisms involved in the metastasis of deadly “triple negative” breast cancers (TNBC). These tumors are extremely difficult to treat, frequently return after remission, and are the most aggressive form of …

Agendia’s MammaPrint & BluePrint Tests for Breast Cancer Highlighted at Personalized Medicine Conference

In In The News by Barbara Jacoby

Molecular subtyping provides a more precise prognosis and valuable guidance about the best treatment for early-stage breast cancer, according to a presentation by Neil Barth, M.D., at the prestigious Personalized Medicine World Conference (PMWC). Dr. Barth, a medical oncologist and Chief Medical Officer of Agendia, was a featured speaker at the recently concluded conference. Agendia’s BluePrint® molecular diagnostics assay is …

Scientists propose a breast cancer drug for bladder cancer patients

In In The News by Barbara Jacoby

From: MedicalXpress.com Researchers at Mayo Clinic have found amplification of HER2, a known driver of some breast cancers, in a type of bladder cancer called micropapillary urothelial carcinoma (MPUC) and have shown that the presence of HER2 amplification is associated with particularly aggressive tumors. These findings suggest that administering trastuzumab to MPUC patients with HER2 amplification could improve outcomes, just …

Breast Cancer Survivors Battling Brittle Bones

In In The News by Barbara Jacoby

Breast cancer survivors not benefitting from calcium and vitamin D supplementations (dailyRx News) Breast cancer survivors can have ongoing health challenges after they’ve beaten “The Big C.” Many are on medications that block estrogen, the hormone that drives most breast cancers. These medicines also increase the risk of osteoporosis (brittle bones) and increase the risk of fractures.   A new …

New drug treats breast cancer

In In The News by Barbara Jacoby

The Walter And Eliza Hall Institute Breast cancer researchers Dr Delphine Merino, Dr François Vaillant, Professor Geoff Lindeman, Professor Jane Visvader and colleagues have shown that BH3-mimetic anti-cancer compounds were effective in treating aggressive breast cancers when combined with a conventional chemotherapy drug. Melbourne researchers have discovered that anti-cancer compounds currently in clinical trials for some types of leukaemia could …