By: Josh Friedman From: healio.com Key takeaways: African American women with triple-negative breast cancer had similar tumor mutational landscape as white women and Asian women. Researchers identified two pathways of disease development. Race does not significantly impact tumor mutations of triple-negative breast cancer, suggesting genetics and environmental factors are the likely reasons African American women have greater disease burden. Researchers …
From a Breast Cancer Survivor, the Holidays Are the Perfect Time to Discuss the Family Medical History
View PostAdjuvant Endocrine/Radiation Therapy May Limit Breast Cancer Recurrence
By: Russ Conroy From: cancernetwork.com Administering endocrine therapy or radiation to patients with early-stage breast cancer in the adjuvant setting may reduce locoregional recurrence (LRR) rates, according to findings from a cohort study published in JAMA Network Open.1 Based on univariate analysis, receipt of adjuvant radiotherapy correlated with significantly lower odds of LRR (HR, 0.21; 95% CI, 0.08-0.52; P <.001), …
FDA Says Yes to Cryoablation for Early Breast Cancer
By: Mike Basset From: medpagetoday.com The FDA granted marketing authorization for the ProSense Cryoablation Systemfor small, early-stage breast cancer in older women not suitable for surgery, maker IceCure announced. A minimally invasive tool that destroys tumors by freezing them, the device is indicated for women 70 years and older who have biologically low-risk tumors, no larger than 1.5 cm, and …
Beyond BRCA: Breast cancer genetic risk and treatment
By: Katie Shumake From: stanford.edu BRCA mutations are the most well-known and common hereditary genetic drivers of breast cancer, with women who have a BRCA mutation being 5-8 times more likely to develop the disease. With a risk this high, it makes sense that much of the focus regarding breast cancer risk is on BRCA, but there are other mutations …
Mastectomy may contribute to worse sexual health, psychosocial outcomes
Source: American College of Surgeons From: news-medical.net While mastectomy is often a necessary and life-saving treatment option for many women with breast cancer, the surgery may contribute to worse sexual health, body image, and several other physical and emotional challenges after surgery, according to a new systematic review on the effects of mastectomy in women with breast cancer. Surgeons said …
Study Finds Restoring Order to Dividing Cancer Cells May Prevent Metastasis
From: cornell.edu Triple negative breast cancer (TNBC) is one of the most aggressive and hardest to treat breast cancers, but a new study led by Weill Cornell Medicine suggests a way to stop it from spreading. Researchers have discovered that an enzyme called EZH2 drives TNBC cells to divide abnormally, which enables them to relocate to distant organs. The preclinical …
New Oral SERD Approved for Certain Estrogen Receptor-mutated Breast Cancers
From:aacr.org The FDA has approved imlunestrant for certain patients with advanced ESR1-mutated breast cancer that has progressed following previous endocrine therapy. The U.S. Food and Drug Administration (FDA) has approved imlunestrant (Inluriyo) for the treatment of adult patients with advanced or metastatic breast cancer that expresses the estrogen receptor (ER), does not overexpress human epidermal growth factor receptor 2 (HER2), …
Breast Cancer Is Rising in Young People: 4 Possible Reasons Why
By:Bec Roldan From: .breastcancer.org Changes to our lifestyle and environmental exposures could be making younger people more susceptible to breast cancer. in the living room, mesmerized by the fire trucks across the street putting out a small fire, and her husband worked quietly in the other room. “We got your results back from the biopsy. Could you come into the …