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Cardiovascular disease and mortality risk in women with breast cancer

In In The News by Barbara Jacoby

By: Coco Davis From: fredhutch.org Thanks to advances in breast cancer treatments, there are more than 3.8 million survivors of female breast cancer.  Women with invasive breast cancer have a 5-year survival rate of 90%. Although there are decreased rates of breast cancer-specific mortality, there has been an increase in cardiovascular and cerebrovascular disease-specific mortality in women with a history …

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Elacestrant Benefit in Breast Cancer, but Compared to What?

In In The News by Barbara Jacoby

By:  M. Alexander Otto, PA, MMS From: .medscape.com Questions are now being asked about the comparator arm of a phase 3 trial in advanced breast cancer in which the investigational drug elacestrant (developed by Menarini/Radius Health) showed enough benefit for the companies to consider applying for approval from the US Food and Drug Administration. Elacestrant is a novel oral selective estrogen …

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Menopausal Hormone Therapy Formulation & Breast Cancer Risk

In In The News by Barbara Jacoby

From: physiciansweekly.com For a study, researchers sought to determine if the formulation of menopausal hormone treatment (HT) utilized affected the increased risk of breast cancer. Using data from the UK Clinical Practice Research Datalink, investigators conducted a population-based case-control study of women aged 50 and up. Women with incident breast cancer were matched (1:10) to a control group of women …

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Social stress factors have a direct impact on cellular mechanisms that drive deadly breast cancer

In In The News by Barbara Jacoby

Source: Duke Health From: news-medical.net Chronically stressful conditions of daily life such as racism, pollution and poverty have a direct impact on the cellular mechanisms that drive lethal, invasive forms of breast cancer, according to a study led by Duke Cancer Institute researchers. Publishing June 13 in the journal npj Breast Cancer, the findings provide insight into one of the …

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How to be your own breast cancer advocate: 5 practical and preventive tips that can save your life

In In The News by Barbara Jacoby

By: Ashima Sharda Mahindra From: timesnownews.com Worldwide, one in eight women are diagnosed or will be diagnosed with breast cancer in their respective lifetimes, say experts. The numbers are depressing but proper measures can prevent the occurrence of this deadly disease. Prevention is better than cure. But prevention begins with knowledge. Women who are at an increased risk of breast …

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Is contrast mammo or contrast MRI best for breast cancer?

In In The News by Barbara Jacoby

By: By Kate Madden Yee From: auntminnie.com Contrast-enhanced mammography (CEM) and contrast-enhanced MRI (CE-MRI) show comparable performance when it comes to identifying breast cancer, but CE-MRI is more sensitive, a study published June 7 in Radiology has found. Yet even if CE-MRI is more sensitive — particularly in women with dense tissue — that doesn’t mean that it’s the best …

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Ancestry-specific genetic risk examined for triple-negative breast cancer

In In The News by Barbara Jacoby

From: medicalxpress.com Women of African ancestry more often have a personal history of triple-negative breast cancer (TNBC), but the magnitudes of gene-specific risks for TNBC are similar across different racial/ethnic groups, according to a study presented at the annual meeting of the American Society of Clinical Oncology, held from June 3 to 7 in Chicago. Michael J. Hall, M.D., from …

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UCSF and I-SPY 2 Breast Cancer Researchers Develop Newly Redefined Breast Cancer Response Subtypes

In In The News by Barbara Jacoby

Source Quantum Leap Healthcare Collaborative From: PR Newswire Improved Classifications May Increase Precision in Targeted Therapies Research scientists and statisticians from UC San Francisco have developed improved biomarker classifications as part of their research results in the I-SPY 2 trial for high-risk breast cancer patients. The new cancer response subtypes reflect responsiveness to drug treatments and are intended to help …

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Counting metastatic lymph nodes is better for determining prognoses of solid tumors

In In The News by Barbara Jacoby

Source: Cedars-Sinai From: news-medical.net Patients newly diagnosed with cancer typically focus on one question, eclipsing all others: “What is my prognosis?” Determining a cancer patient’s prognosis-; the likely course and outcome of their disease-; typically involves staging the lymph nodes, a process that examines factors such as the lymph node’s size, location and how far the cancer has extended beyond …

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KEYNOTE-522: Neoadjuvant and Adjuvant Pembrolizumab in TNBC

In In The News by Barbara Jacoby

By: Joyce A. O’Shaughnessy, MD, Sara A. Hurvitz, MD From: onclive.com Expert perspectives on adjuvant and neoadjuvant use of pembrolizumab in the KEYNOTE-522 study in triple-negative breast cancer. Transcript: Joyce A. O’Shaughnessy, MD: Let’s go on to the third data set, which is the KEYNOTE-522. We’re finally getting a big advance for patients with high-risk TNBC [triple-negative breast cancer] in …