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Biomarker could help guide cancer therapy, avoid drug resistance

In In The News by Barbara Jacoby

By: Anne Trafton From: mit.edu MIT biologists have identified a new biomarker that can reveal whether patients with a particularly aggressive type of breast cancer will be helped by paclitaxel (commercially known as Taxol), one of the drugs most commonly used to treat this cancer. The findings could offer doctors a new way to choose drugs for this type of …

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Gene ‘Signature’ Could Lead to Early Cancer Test

In In The News by Barbara Jacoby

By: Maggie Fox From: nbcnews.com Researchers have found a genetic “signature” common to five different types of cancer and hope it might be a step towards an early blood test for cancer in general. It’s not a genetic mutation but a change in the genetic function called methylation, the team at the National Human Genome Research Institute, one of the …

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Vascular ALK1 May Be Biomarker Indicating Breast Cancer Metastases

In In The News by Barbara Jacoby

From: medicalresearch.com MedicalResearch.com Interview with: Kristian Pietras, Ph.D. Göran & Birgitta Grosskopf Professor of Molecular Medicine Strategic Director of Cancer Research Lund University Dept of Laboratory Medicine Lund Div of Translational Cancer Research Lund, Sweden Medical Research: What is the background for this study? What are the main findings? Dr. Pietras: Breast cancer is the largest malignant disease among women …

Risk Of Breast Cancer Recurrence After Tamoxifen Treatment Predicted By Biomarker

In In The News by Barbara Jacoby

From Medical News Today A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment. In their report published online in the Journal of the National Cancer Institute, Massachusetts General Hospital (MGH) Cancer Center investigators describe finding …