By: Johns Hopkins From; scitechdaily.com A bacterium best known for causing gum disease may also influence how breast cancer begins and spreads. A team at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy reports that a mouth-dwelling bacterium tied to periodontal disease could help set breast cancer in motion and make it more aggressive. In …
Stressors affect systemic inflammation, tumor aggressiveness in breast cancer
By: Elana Gotkine From: medicalxpress.com For women with breast cancer, stressors are associated with deleterious alterations to the systemic and tumor immune environment, according to a study published online Feb. 14 in JAMA Network Open. Alexandra R. Harris, Ph.D., M.P.H., from the National Institutes of Health in Bethesda, Maryland, and colleagues examined the proteomic, transcriptomic, and genomic effects associated with …
African genetic ancestry may be linked to breast cancer aggressiveness
By: Erin T. Welsh, MA From: healio.com Key takeaways: Higher African ancestry was linked to higher odds of estrogen receptor-negative tumors and triple-negative breast cancer. Neighborhood socioeconomic status increases were linked to lower all-cause mortality. Higher African genetic ancestry was associated with more aggressive tumor subtypes at diagnosis among Black women with breast cancer, according to cohort study findings published …