By: M. Alexander Otto, PA, MMSc From: medscape.com MRI can identify patients with HER2-positive breast cancer who don’t need a full course of neoadjuvant chemotherapy, letting them avoid the toxicity of unnecessary treatment while preserving 3-year event-free survival, new trial findings suggest. The study, published in The Lancet Oncology, found that patients had “excellent” outcomes even if they received only …
New Insights into Breast Cancer Metastasis
Key Takeaways Breast cancer frequently spreads to other tissues, leading to worse outcomes for patients UC San Diego researchers have discovered a new way the body helps prevent the spread of breast cancer Results could help yield new treatment approaches and also suggest risks for people taking certain medications A study by researchers at the University of California San Diego …
Low Breast Cancer Recurrence Rate With Radiotherapy Tailored to Nodal Response
By: Charles Bankhead From: medpagetoday.com Ten years after tailored radiotherapy (RT) for breast cancer, fewer than 3% of patients had locoregional recurrences (LRR), most during the first 5 years, a Dutch registry study showed. The overall LRR of 2.9% did not differ significantly across subgroups of patients with low-, intermediate-, or high-risk disease or between the risk groups. Both the …
Aggressive BP Control Linked to Lower Mortality in mBC
By: Jennifer Kulpa From: clinicaloncology.com Hypertension is one of the most common comorbidities in patients with metastatic breast cancer (mBC), yet blood pressure (BP) management is often deprioritized in the context of stage IV disease. A new study suggests that both the choice of antihypertensive regimen and the consistency of use may influence overall mortality in this population (Cancer Med …
Breast Cancer Hijacks the Lung Repair System to Fuel Tumor Growth, Study Finds
By: Laura Kelley From: cuanschutz.edu Researchers at the CU Anschutz Cancer Center have discovered how breast cancer cells that spread to the lungs may take advantage of the body’s natural healing response and how a commonly used drug might slow that process. They found that breast cancer cells that spread to the lungs trigger the lung’s normal repair system, creating …
Symptoms of Late Stage Metastatic Breast Cancer
From: healthline.com Breast cancer that has spread to other parts of your body may start to cause new symptoms, depending on the location of the metastases. As symptoms develop or progress, treatment and care may also need to change. Metastatic breast cancer occurs when cancer that started in the breast spreads to another part of the body. It’s also known …
Delaying Pegfilgrastim May Curb Bone Pain in Breast Cancer
By; Frederik Joelving From: medscape.com Women given pegfilgrastim to prevent myelosuppression after chemotherapy for breast cancer often develop bone pain — but a small clinical trial suggests that delaying the drug by just one extra day can lessen the side effect. Researchers found that beginning pegfilgrastim (Neulasta) on day 3 after the final chemotherapy dose reduced the incidence of severe …
Alternative Treatments are Linked to Lower Breast Cancer Survival
By: Stacy Kish From: yale.edu Advances in early screening mammography and new, targeted treatments have reduced overall mortality and recurrence in breast cancer. Yet, despite these advances in traditional treatment options, some patients continue to choose complementary and alternative medicine (CAM), such as dietary supplements, mind and body approaches, and acupuncture. “I was moved by a patient discussing her decision …
Pyrotinib-Based Dual Anti-HER2 Regimen Extended Survival in Metastatic Breast Cancer
By: Mary Ellen Schneider From: cancertherapyadvisor.com Pyrotinib plus trastuzumab and docetaxel outperformed trastuzumab and docetaxel alone as an initial treatment for HER2-positive metastatic breast cancer, according to findings published in the BMJ. The final analysis of the phase 3 PHILA taril (NCT03863223) demonstrated significant improvements in both progression-free survival (PFS) and overall survival (OS). “Pyrotinib, a small molecule, irreversible, pan-HER …
Strategy to detect infections early after breast reconstruction may have ‘broad impact’
By: Mark Leiser From: healio.com Metabolites in tissue fluid offer important clues that could help predict infection risk among women who undergo breast reconstruction after cancer. Metabolites — small molecules created or broken down during cellular processes such as energy production or cell signaling — include specialized small molecules produced by bacterial pathogens. Analyses of metabolite patterns among women who …