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Engineered killer T cells could provide long-lasting immunity against cancer

In In The News by Barbara Jacoby

UCLA researchers use stem cells to engineer cells that attack human tumors in mice They’ve been called the “special forces” of the immune system: invariant natural killer T cells. Although there are relatively few of them in the body, they are more powerful than many other immune cells. In experiments with mice, UCLA researchers have shown they can harness the …

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Drug accelerates blood system’s recovery after chemotherapy, radiation

In In The News by Barbara Jacoby

From: ucla.edu A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants. The study, published in Nature Communications, also sheds light on the basic biology …

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Personalized gene-edited immune cell therapy for patients with solid cancers: New data establishes approach for verifying patient-specific cancer mutation targets

In Clinical Trials by Barbara Jacoby

Source: PACT Pharma From: PR Newswire – PACT’s gene-edited T cells were observed to kill tumor cells by targeting patient-specific tumor mutation targets in non-clinical testing – The company is launching clinical studies of personalized targeted immune cell therapy for patients with solid cancers PACT Pharma, a leader in the fields of cancer immunology and cell therapy in collaboration with …

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Adding targeted therapy to treatment extends lives of those with metastatic breast cancer

In Clinical Trials by Barbara Jacoby

Source: UCLA Jonsson Comprehensive Cancer Center From: eurekalert.org A UCLA-led study has found that using a drug called ribociclib in combination with a common hormone therapy may help premenopausal women with the most common type of breast cancer live longer than if they only receive the hormone therapy. Ribociclib is considered a cyclin-dependent kinase inhibitor that works by blocking the …

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Science Says: Chemo Brain Is Real.

In In The News by Barbara Jacoby

UCLA Study Shows Breast Cancer Treatments Can Cause Cognitive Impairment By: Brittany Shoot From: fortune.com A new study from researchers at the University of California, Los Angeles shows that some cancer patients can experience cognitive decline after chemotherapy and radiation treatments. It’s commonly thought that cancer treatments may accelerate biological aging in cells. Specifically seen in this new UCLA study …

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Researchers find adult stem cell characteristics in aggressive cancers from different tissues

In In The News by Barbara Jacoby

By: Tiare Dunlap From: ucla.edu Study could lead to new treatments for advanced epithelial cancers such as lung and prostate cancers UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues — which line all of the organs and cavities inside the body — and the cells that drive aggressive epithelial cancers. Their …

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UCLA researchers develop synthetic T cells that mimic form, function of human version

In In The News by Barbara Jacoby

By: Brianna Aldrich From: newsdesk@redingtoninc.com Discovery could be a step toward developing treatments for cancer and autoimmune diseases UCLA researchers have developed synthetic T lymphocytes, or T cells, that are near-perfect facsimiles of human T cells. The ability to create the artificial cells could be a key step toward more effective drugs to treat cancer and autoimmune diseases and could lead to …

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How California can break down barriers to breast cancer treatment

In In The News by Barbara Jacoby

Venetia Lai From: ucla.edu UCLA fact sheets recommend changes to help patients and survivors – particularly low-income women – who face serious obstacles to care More than 29,000 women in California will be diagnosed with breast cancer in 2018. Many of them — especially low-income women, who suffer the worst survival rates — will face economic, emotional and structural obstacles …

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Many Breast Cancer Patients Receive More Radiation Therapy Than Needed

In In The News by Barbara Jacoby

By: Liz Szabo From: npr.org When Annie Dennison was diagnosed with breast cancer last year, she readily followed advice from her medical team, agreeing to harsh treatments in the hope of curing her disease. “You’re terrified out of your mind” after a diagnosis of cancer, said Dennison, 55, a retired psychologist from Orange County, Calif. In addition to lumpectomy surgery, …

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Early cancer detection through saliva is real health care reform

In In The News by Barbara Jacoby

By: Joel Strom From: ocregister.com While the public and media focus their attention on stalled health care reform at the public policy level, they overlook real health care reforms that could significantly improve public health, increase access and lower costs. Consider the recent major breakthrough in early cancer detection using saliva. With the exception of advancements for certain cancers, including …