Source: University of California – San Diego From: news-medical.net Researchers at University of California San Diego have identified a previously unrecognized treatment target for triple‑negative breast cancer (TNBC), the most aggressive subtype of breast cancer. Their new study reveals that a protein called PUF60 plays an essential role in helping TNBC cells grow and survive by controlling how key genes …
New Antibody Halts One of the Deadliest Breast Cancers
By: Medical University of South Carolina From: scitechdaily.com Scientists have uncovered a powerful new antibody that disrupts a key protein helping triple-negative breast cancer survive and evade immunity. Triple-negative breast cancer (TNBC) is considered one of the most aggressive and difficult forms of breast cancer to treat. It grows rapidly, tends to spread at an early stage, and does not …
Study reveals biological insights into triple negative breast cancer
Source:Louisiana State University Health Sciences Center From: news-medical.net Researchers at the LSU LCMC Health Cancer Center have published groundbreaking findings in NPJ Breast Cancer that sheds new light on triple-negative breast cancer (TNBC), one of the most aggressive forms of breast cancer. The National Cancer Institute (NCI)-funded study, led by Dr. Lucio Miele, Director of the LSU LCMC Health Cancer …
Scientists May Have Found a Way to Stop One of the Deadliest Breast Cancers
By Oregon Health & Science University From: scitechdaily.com Scientists at Oregon Health & Science University (OHSU) have created a new molecule that could provide a promising path forward in treating some of the most difficult cases of triple-negative breast cancer, a particularly aggressive form of the disease that currently lacks effective therapies. The findings, published in Cell Reports Medicine, detail …
Tracking RNA levels reveals new clues in triple-negative breast cancer progression
By: Jen A. Miller, Cold Spring Harbor Laboratory From: medicalxpress.com When researchers look for potential cancer therapy targets, they typically go after protein-coding genes that participate in disease progression. Disrupt them and negate whatever role they play in cancer’s development or spread. Researchers at Cold Spring Harbor Laboratory (CSHL) have also been working on another kind of target. They’re studying …
New type of immunotherapy could change the treatment plan for triple-negative breast cancer
Source: University of California – Los Angeles From: news-medical.net Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main targets that make other types of breast cancers more treatable with powerful therapies. UCLA researchers have developed a novel therapy that could fundamentally change the treatment plan for this deadly disease. …
Tumor mutations of triple-negative breast cancer similar across races
By: Josh Friedman From: healio.com Key takeaways: African American women with triple-negative breast cancer had similar tumor mutational landscape as white women and Asian women. Researchers identified two pathways of disease development. Race does not significantly impact tumor mutations of triple-negative breast cancer, suggesting genetics and environmental factors are the likely reasons African American women have greater disease burden. Researchers …
Landmark study maps mutational landscape of triple-negative breast cancer in African American women
Source: Roswell Park Comprehensive Cancer Center From: news-medical.net Triple-negative breast cancer (TNBC), the deadliest breast cancer subtype, disproportionately affects African American women – but until now, they were underrepresented in genomic studies aimed at identifying the genetic mutations driving the disease. A landmark study led by researchers at Roswell Park Comprehensive Cancer Center and collaborating institutions fills that knowledge gap. …
Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer
Source: University of Mississippi From: news-medical.net Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease. A team of researchers from the University of Mississippi found that coating nanoparticles containing cancer therapies in a sugar-like substance makes them more effective in targeting this cancer. They published their …
Redefine Body Confidence When You Have Metastatic Triple-Negative Breast Cancer
By: Julia Califano From: everydayhealth.com When you’re living with metastatic triple-negative breast cancer (mTNBC), the journey is about not only managing the illness, but also navigating the physical and emotional changes that come with ongoing treatment. Hair loss, skin changes, and weight fluctuations are common side effects of treatments such as chemotherapy and immunotherapy. These physical changes can affect how …