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A master switch controls aggressive breast cancer

In In The News by Barbara Jacoby

Salk scientists who discovered that aggressive breast cancer reprises pathways found in fetal cells have identified genetic master switch for process A team at the Salk Institute has identified a master switch that appears to control the dynamic behavior of tumor cells that makes some aggressive cancers so difficult to treat. The gene Sox10 directly controls the growth and invasion …

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New approach for hard-to-treat BRCA breast cancer shrinks tumours twice as fast

In In The News by Barbara Jacoby

By: Henry Bodkin From: telegraph.co.uk Scientists have expressed optimism for women with hard-to-treat breast cancer after a new chemotherapy regime proved it can shrink tumours twice as fast as normal methods. Women with aggressive “triple-negative” disease fare much better on a non-standard chemotherapy drug if they have inherited BRCA gene mutations, the results of a trial showed. Currently most patients with this type of breast cancer, …

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Biomarker could help guide cancer therapy, avoid drug resistance

In In The News by Barbara Jacoby

By: Anne Trafton From: mit.edu MIT biologists have identified a new biomarker that can reveal whether patients with a particularly aggressive type of breast cancer will be helped by paclitaxel (commercially known as Taxol), one of the drugs most commonly used to treat this cancer. The findings could offer doctors a new way to choose drugs for this type of …

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Researchers reveal potential for exploring new treatment options for triple-negative breast cancer

In In The News by Barbara Jacoby

From: news-medical.net Researchers from Caris Life Sciences® and Fox Chase Cancer Center – Temple Health announced the presentation of two studies revealing the potential for exploring new therapeutic options for triple-negative breast cancer (TNBC) at the 2015 San Antonio Breast Cancer Symposium (SABCS). Researchers used Caris Molecular Intelligence®, Caris’s panomic, comprehensive tumor profiling service, to assess biomarker profiles in subsets …

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New Cancer Report May Help Doctors ID Which Patients More At Risk

In In The News by Barbara Jacoby

By: Jessica Firger From: cbsnews.com At Ricki Fairley’s annual check-up in 2012, doctors found a tiny lump. She was diagnosed with triple negative breast cancer, a less common and more aggressive form of the disease that has very few treatment options. Approximately 15 percent of all breast cancer cases are categorized as triple negative. Triple negative breast cancer can be …

This breast cancer scares patients, challenges doctors

In In The News by Barbara Jacoby

By: Shari Rudavsky From: indystar.com When Tonya Trotter first felt a quarter-size knot in her breast, she didn’t rush to get a mammogram. Over the next few months, the lump grew to the size of a tennis ball. But it was the sharp pain in her breast that finally persuaded her to go to the emergency room in August 2012. …