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CAR-T Trial for Triple-Negative Breast Cancer Under Way

In Clinical Trials by Barbara Jacoby

By: Christina Bennett, MS From: cancertherapyadvisor.com A phase 1 trial (ClinicalTrials.gov Identifier: NCT02706392) is underway at Fred Hutchinson Cancer Research Center to evaluate a chimeric antigen receptor (CAR) T cell therapy in patients with cancer who have receptor tyrosine kinase-like orphan receptor 1 (ROR1)-positive disease, including those with triple-negative breast cancer (TNBC). The trial progress and early data for patients …

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New Clinical Trial for Triple-Negative Breast Cancer at Sylvester Comprehensive Cancer Center

In Clinical Trials by Barbara Jacoby

Vaccine Designed to Prevent Recurrence Panic washed over Jackie Barrett when she first received her breast cancer diagnosis. “My eyes went dark. I couldn’t hear anything. It was like a train was coming at me,” she says. Jackie’s oncologist explained that her type of breast cancer is called triple-negative because it does not have receptors for estrogen, progesterone or the …

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Norwalk Hospital reports positive results with breast cancer clinical trials

In Clinical Trials by Barbara Jacoby

By: Kevin Zimmerman From: westfaironline.com Four cutting-edge breast cancer clinical trials recently launched at Norwalk Hospital’s C. Anthony and Jean Whittingham Cancer Center are giving hope to patients diagnosed with triple negative breast cancer, an aggressive form of the disease that cannot be treated with hormone therapies or other cancer-fighting drugs. “We started about six months ago,” said Dr. Linda …

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Immunotherapy trial offers new hope for people with aggressive breast cancer

In Clinical Trials by Barbara Jacoby

Source: qmul.ac.uk From: news-medical.net There is new hope for people with an aggressive type of breast cancer, as an immunotherapy trial shows for the first time that lives can be extended in people with triple-negative breast cancer. New research led by Queen Mary University of London and St Bartholomew’s Hospital has shown that by using a combination of immunotherapy and …

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Existing drug may treat triple-negative breast cancer

In In The News, Uncategorized by Barbara Jacoby

By: Ana Sandoiu From: medicalnewstoday.com The existing drug estradiol can inhibit tumor growth in a subtype of triple-negative breast cancer. The researchers may soon test the repurposed drug in a phase II clinical trial. Triple-negative breast cancer is an aggressive form of breast cancer wherein tumors lack expression of three proteins. The three are estrogen receptor, progesterone receptor, and human …

Western Connecticut Health Network Site Launches Breast Cancer Clinical Trials through Collaboration with Memorial Sloan Kettering Cancer Center

In Clinical Trials by Barbara Jacoby

As part of a pioneering cancer-care collaboration between Norwalk Hospital and Memorial Sloan Kettering Cancer Center, clinical trials studying new breast cancer therapies are now open in Fairfield County. Four cutting-edge breast cancer clinical trials have launched at Norwalk Hospital, part of the Western Connecticut Health Network. The breast cancer clinical trials are an extension of Memorial Sloan Kettering Cancer …

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Cancer docs say ‘superblood’ may work against deadly malignancies

In In The News by Barbara Jacoby

By: David Cox From: nbcnews.com Cancer care has seen its share of false dawns in recent years, with many new drugs failing to live up to their early promise. But now there’s great excitement over so-called “superblood” — red blood cells that have been chemically modified to deliver cancer-killing drugs like L-asparaginase, an enzyme that blocks the nutrients cancer cells …

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Could THIS combination cure breast cancer? ‘

In In The News by Barbara Jacoby

By: Stephen Matthews From: dailymail.co.uk A combination of immunotherapy and a virus could treat aggressive breast cancer, an ‘absolutely amazing’ study has revealed. Breakthrough research showed the pairing cured up to 90 per cent of mice plagued by triple negative breast cancer – deemed the deadliest form. Canadian scientists are hopeful the findings will lead to a potential cure, as …

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Researchers repurpose immune-activating cytokine to fight breast cancer

In In The News by Barbara Jacoby

Source: Case Western Reserve University From: sciencedaily.com The most lethal form of breast cancer could have a new treatment option, according to new research out of the Case Comprehensive Cancer Center at Case Western Reserve University School of Medicine. In the Proceedings of the National Academy of Sciences, researchers showed triple-negative breast cancer cells are highly vulnerable to interferon-β — …