By: Ryan Scott From: onclive.com Robust phase 3 trial data have led to the integration of CDK4/6 inhibitors into the hormone receptor–positive, HER2-negative breast cancer treatment paradigm, and the continued emergence of data have helped answer selection and sequencing questions about agents such as ribociclib (Kisqali), abemaciclib (Verzenio), and palbociclib (Ibrance), according to Lubna Naaz Chaudhary, MD, MS. “In our …
Thyroid Dysfunction is Common in Women With Breast Cancer Following Radiation Therapy
By: Rob Dillard From: docwirenews.com Thyroid and parathyroid dysfunction is common among women with breast cancer (BC) following radiotherapy (RT), according to a study published in the Canadian Oncology Nursing Journal. “The current advances in (RT) have improved the outcome of breast cancer (BC) patients. Despite its therapeutic benefits, the iatrogenic toxicities of RT and its impact on BC survivors …
MSU lab develops promising breast cancer model
From: msu.edu A Michigan State University researcher’s new model for studying breast cancer could help scientists better understand why and where cancer metastasizes. Professor Eran Andrechek who teaches in the MSU Department of Physiology, has been researching the E2F5 gene, of which little is known, and its role in the development of breast cancer. Based on findings from Andrechek’s lab, the loss of …
Social Determinants of Health Matter When Treating Patients With Breast Cancer
Author(s): Maria Roberts, PharmD, Angie Oster, PharmD From: pharmacytimes.com Key Takeaways Breast cancer incidence is rising, with invasive ductal carcinoma as the most common type, necessitating personalized treatment plans based on tumor characteristics and staging. Social determinants of health (SDOH) significantly influence breast cancer treatment adherence and outcomes, with digital and health literacy being major factors. Rates of breast cancer …
Which First-Line Breast Cancer Therapy Is Right for Me?
From: healthline.com You have several options for treating breast cancer, including chemo, radiation, hormone, and targeted therapies. Certain therapies may be more effective for specific types of breast cancer. After diagnosis, knowing where to turn next with your breast cancer treatment can be a tough decision. But understanding the different types of therapies available and your stage of breast cancer …
Researchers develop new approach to predict immunotherapy response in breast cancer patients
Source: Johns Hopkins Medical From: news-medical.net Using computational tools, researchers from the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a method to assess which patients with metastatic triple-negative breast cancer could benefit from immunotherapy. The work by computational scientists and clinicians was published Oct. 28 in the Proceedings of the National Academy …
Scientists explore HDAC6 inhibition for breast cancer treatment
By: University of Sharjah From: medicalxpress.com Scientists from the University of Sharjah say they have good news for breast cancer patients, particularly those afflicted with the most aggressive types of the malignant tumor known as triple-negative breast cancer. The study, published in the European Journal of Pharmacology, provides “new ways for the treatment of the special type of breast cancer called triple-negative breast …
Surgical Innovations Help Personalize Breast Cancer Treatment, Improve Quality of Life
From: newswise.com There are two surgical options to treat breast cancer: lumpectomy and mastectomy. But there are many more reasons why women choose one over another, says Sarah McLaughlin, M.D., a breast surgical oncologist and chair of the Department of Surgery at Mayo Clinic in Jacksonville, Florida. “Some of that can be cancer-based, some of it can be family history and …
5 questions to ask a breast cancer surgeon
From: roswellpark.org What to learn about their experience, advanced options they provide and more — before deciding where to seek cancer care. If you’ve been diagnosed with breast cancer, surgery will likely be a primary part of your treatment. You’ll want to choose a surgeon and cancer center with the tools and expertise to deliver the best outcomes for your …
RK-33 May Be Significant in Treatment of Breast Cancer Bone Metastasis
By: Gillian McGovern From: pharmacytimes.com Key Takeaways RK-33 targets DDX3, an RNA helicase elevated in cancer cells, to inhibit breast cancer bone metastasis. In mouse models, RK-33 eliminated bone metastases and prevented further cancer spread without significant adverse effects. A study published in Cancer Letters demonstrated new promise in the treatment of breast cancer bone metastasis, or breast cancer that …