Source: Oncotarget From: news-medical.net A new editorial paper was published in Oncotarget’s Volume 14 on June 12, 2023, entitled, “Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?” A vast majority of breast cancers (~70%) are estrogen receptor-alpha positive (ER+), for which endocrine therapy is the common treatment. However, recurrence often occurs leading to tumor progression, metastasis and …
Early-Stage Triple-Negative Breast Cancer: Optimizing Therapy
By: Caroline Helwick From: ascopost.com The management of early-stage triple-negative breast cancer has been evolving at a fast pace, thanks largely to the discovery that immune checkpoint blockade can be effective in this subtype. At the 2023 Miami Breast Cancer Conference, Priyanka Sharma, MD, Professor of Medicine, University of Kansas Medical Center, took a sweeping look at the data that …
Therapeutic Advances Rapidly Expand the Breast Cancer Armamentarium Across Subtypes
By: Courtney Flaherty From: onclive.com An increasing focus on antibody-drug conjugates (ADCs) for HER2-positive breast cancer signals a potential shift in the standard of care (SOC) for this population. Several investigations have also confirmed the efficacy of CDK4/6 inhibitors in the first- and second-line treatment of hormone receptor (HR)–positive, HER2-negative breast cancer. Yet patients with historically poor prognosis require further …
Breast cancer patients get proton beam therapy on NHS in world-first trial
By: Andrew Gregory From: theguardian.com Three breast cancer patients have undergone pioneering proton beam therapy for the first time on the NHS as part of a world-first trial. The hi-tech treatment targets tumours far more precisely than conventional radiotherapy, suiting patients with difficult-to-treat growths in critical areas. The NHS has previously used proton beam therapy to treat patients with tumours …
Breast-conserving therapy may be viable option for multiple ipsilateral breast cancer
From: healio.com Lumpectomy followed by radiation therapy resulted in low rates of local recurrence at 5 years among women with multiple ipsilateral breast cancer, according to phase 2 study results. The findings — presented at San Antonio Breast Cancer Symposium — also indicated women with two or more malignant lesions in the same breast considering breast-conserving therapy may benefit from …
Cancer patients with depression have resources
Source: Reuters Health From: foxnews.com Cancer patients who experience depression can use both therapy and lifestyle tools to help support their mental health, according to a new patient resource from the JAMA Oncology journal. People with cancer, as well as their doctors, need to remember that mental health is as important as physical health for these patients, the authors note. …