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Lower dose of oestrogen receptor modulator seems to reduce risk of breast cancer

In Clinical Studies News by Barbara Jacoby

Source: Karolinska Institutet From: eurekalert.org While the drug tamoxifen reduces the risk of developing breast cancer and prevents recurrence, the side-effects cause many women to discontinue their treatment. A study involving researchers at Karolinska Institutet in Stockholm has now found that a much lower dose than the standard produces a good effect with fewer adverse reactions in women who have …

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Adjuvant Hormonal Therapy Adherence Low Among Commercially Insured Patients With Breast Cancer

In Clinical Studies News by Barbara Jacoby

By: Janelle Bradley From: .journalofclinicalpathways.com Adjuvant hormonal therapy adherence at 5 years are low among commercially insured patients with breast cancer, according to a recent study (JCO Oncol Pract. 2021;OP2000248. doi:10.1200/OP.20.00248). “Tamoxifen and aromatase inhibitors are used as adjuvant hormonal therapy for early-stage hormone receptor-positive (HR+) breast cancer,” wrote Hui Zhao, PhD, Department of Health Services Research, The University of …

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Study Characterizes Risk For New Persistent Opioid Use in Patients Undergoing Curative-Intent Treatment For Breast Cancer

In In The News by Barbara Jacoby

By: Leah Lawrence From: cancertherapyadvisor.com Although a large percentage of women undergoing curative-intent treatment for breast cancer were prescribed opioids, only a small number developed new persistent opioid use, according to data from a retrospective study reported in the Journal of the National Comprehensive Cancer Network.1 However, among the smaller number of patients prescribed benzodiazepines, new persistent use after treatment …

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Identification of Tamoxifen Resistance Markers Can Play Role in Breast Cancer Treatment Planning

In Clinical Studies News by Barbara Jacoby

By: Rutgers Cancer Institute of New Jersey From: newswise.com One common challenge of cancer therapy is when cancer cells don’t respond to a drug that is usually able to kill or weaken them, known as treatment resistance. Tamoxifen is a drug that blocks the activity of estrogen in the breast, commonly used to treat patients with estrogen-receptor (ER) positive breast cancer. In …

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Are Breast Cancer Risk-Reducing Medications Right For You?

In In The News by Barbara Jacoby

From: breastadvocateapp.com With the exception of skin cancer, breast cancer is the most common cancer among American women, and the second leading cause of cancer deaths in the US. Women with a high risk of developing breast cancer have the option of lowering their risk by taking certain medications. The US Preventive Services Task Force (USPSTF) recently made two updates …

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Breast cancer gel being tested in Chicago; Northwestern recruiting patients for clinical trial

In Clinical Studies News by Barbara Jacoby

By: Judy Hsu From: abc7chicago.com Researchers in Chicago and across the country are hoping to prove a topical gel can treat breast cancer. If successful, it would produce a safer alternative to a common breast cancer medication that some patients are reluctant to take. It’s the first time tamoxifen, a drug used for decades to reduce the risk and recurrence …

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SABCS 2018: Happy and Hopeful about Less Hormone Therapy

In In The News by Barbara Jacoby

By Karuna Jaggar, Executive Director From: bcaction.org The strong response gets at how much women hate taking tamoxifen. Tamoxifen is the oldest and most common breast cancer treatment and was made more than 50 years ago. It’s cheap (at around $1 a day) and effective. Treatment with tamoxifen is usually a daily pill for five years (and up to 10 …

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There is need for chemoprevention options for women with breast cancer, says GlobalData

In In The News by Barbara Jacoby

Breast cancer is the most common female cancer worldwide. Women who are at high-risk of developing the disease have few chemoprevention options and often resort to invasive prophylactic surgery. Leading data and analytics company GlobalData, feels that new non-invasive chemoprevention strategies for women who are genetically predisposed to breast cancer are sorely needed. While selective estrogen receptor modulators (SERMs) such …

Skin gel new ammunition in fight against breast cancer

In In The News by Barbara Jacoby

By Caelainn Hogan From: washingtonpost.com A gel containing the drug tamoxifen and applied to the skin was as effective in reducing the growth of breast cancer cells in women with noninvasive cancer as the pill form of the medication — and it caused fewer side effects, according to a new study. The paper, published Tuesday in Clinical Cancer Research, a …

Twice the Tamoxifen Backed for Breast Cancer Patients

In In The News by Barbara Jacoby

By:  Hope T. Jackson, MD From: abcnews.go.com One of the top cancer groups in the U.S. is urging breast cancer patients to take the drug tamoxifen for 10 years after treatment with surgery, chemo or radiation – effectively doubling the previously recommended five years on the drug. Tamoxifen targets the hormones estrogen and progesterone, which are important in the development …