By: Liam Davenport From: medscape.com TOPLINE: Patients with hormone receptor positive (HR+), HER2-negative (HER2-), high-risk early breast cancer experience a significant overall survival benefit with the addition of the CDK4/6 inhibitor abemaciclib to endocrine therapy, as well as a reduction in rates of metastatic disease, according to an analysis of data from the monarchE trial presented at the ESMO Congress …
‘This is important’: Mammograms significantly improve survival beyond 80 years of age
By: Josh Friedman From: healio.com Key takeaways: Women diagnosed with breast cancer at 80 years and older had significantly improved survival if they had recent mammograms. Mammograms discovered smaller tumors at less advanced stages. Older age should not stop women from getting mammograms. A retrospective analysis found women with breast cancer aged at least 80 years had a 55% lower …
An Understudied Type of Breast Cancer Poses a Lurking Threat
By: Mark Harden From: cuanschutz.edu University of Colorado Cancer Center member Matthew Sikora, PhD, is a national leader in research into an understudied subtype of breast cancer that’s on the rise in American women, is often more difficult to detect than other forms of breast cancer, and has sharply lower survival rates several years after diagnosis than the most common …
The Role of Invasive Disease-Free Survival in Breast Cancer Research
By: Stephanie L. Graff, MD From: targetedonc.com Experts explore the potential of invasive disease-free survival as a key metric in breast cancer trials, aiming to accelerate treatment approvals. In an interview with Targeted Oncology, Stephanie L. Graff, MD, FACP, FASCO, director of the Breast Oncology Program at Brown University Health Cancer Institute, and co-leader of the Breast Cancer Translational Research …
Adding Aprepitant to Chemo Extends Non-Luminal Breast Cancer Survival
By: Bridget Hoyt From: oncnursingnews.com The addition of the antiemetic aprepitant (Emend) to standard chemotherapy was linked to improved survival outcomes for patients with early non-luminal breast cancers, particularly those with triple-negative breast cancer, according to data published in the Journal of the National Cancer Institute.1 Stratified analyses demonstrated a significant improvement in distant disease-free survival (DDFS) and breast cancer-specific …
Researchers discover a new tissue biomarker for aggressive breast cancer risk and poorer survival
By: National Institutes of Health From: medicalxpress.com Researchers at the National Institutes of Health (NIH) have identified a series of changes in the architecture and cell composition of connective tissues of the breast, known as stromal tissue, that is associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival …
Chest Wall Irradiation Does Not Impact Survival in Breast Cancer
By: Elana Gotkine From: healthday.com For patients with intermediate-risk breast cancer, chest wall irradiation (CWI) after mastectomy does not influence 10-year overall survival, according to a study presented at the annual San Antonio Breast Cancer Symposium, held from Dec. 10 to 13 in San Antonio. Ian Kunkler, M.B., B.Chir., from the University of Edinburgh in the United Kingdom, and colleagues …
Study finds depression can reduce survival among women with breast cancer
By: Carlos Andres López, New Mexico State University From: medicalxpress.com New research from New Mexico State University shows depression can reduce survival rates among American women diagnosed with breast cancer. Jagdish Khubchandani, a professor of public health sciences at NMSU, led a study to understand the long-term impacts of depression among American women with breast cancer. Khubchandani’s study partners included the Kirk Kerkorian …
High breast density tied to impaired recurrence-free cancer survival
By: Amerigo Allegretto From: auntminnie.com Recurrence-free breast cancer survival is less likely in women with high breast density compared to women with low density, according to research published April 18 in The Breast. A team led by Kristina Lång, MD, PhD, from Lund University in Sweden found that these results were especially evident for women with screening-detected cancers. However, they found …
Don’t Rule Out Breast Cancer Surgery for 90-Year-Olds
By: Ed Susman From: medpagetoday.com Primary breast cancer surgery for nonagenarians in good physical shape was associated with improved survival compared with a non-surgical approach, retrospective data from a single center in Italy showed. Among 123 breast cancer patients ages 90 and above, median overall survival from the time of diagnosis reached 54 months for those who underwent mastectomy or …