By Dr. Liji Thomas, MD From: news-medical.net Background Mammographic density (MD) reflects the proportion or amount of fibroglandular tissue in the breast, depending on the measurement method. Fibroglandular tissue contains epithelial and stromal components that can become malignant. Higher mammographic density is associated with a higher risk of breast cancer. MD is assessed in various ways: as percentage density, density …
Baby Tam (Low-Dose Tamoxifen)
By: Jamie DiPolo From:.breastcancer.org Tamoxifen is commonly used to reduce the risk of invasive breast cancer or a recurrence of non-invasive disease if someone has been treated for DCIS, LCIS, or atypical ductal hyperplasia. But because of potential serious risks, including blood clots, endometrial cancer, and stroke, as well as troubling side effects, like hot flashes, many people either don’t …
Can Estrogen Increase Your Risk of Breast Cancer?
From: healthline.com Estrogen itself isn’t always dangerous and is, in fact, a necessary component in human development. However, in some cases, increased estrogen exposure over your lifetime may increase your risk of developing breast cancer. In this article, we take a closer look at estrogen, including when and why it may increase your risk of developing breast cancer and steps …
Breast Cancer Risk Criteria Miss Nearly All Women Who Later Develop Cancer
By: Laura Cowen From: insideprecisionmedicine. Researchers at the University of Cambridge and The Institute of Cancer Research in London have shown that the current UK National Institute for Health and Care Excellence (NICE) breast cancer risk assessment criteria miss over 95% of women under 50 years of age who will develop the disease within 10 years. Compared with the multifactorial …
Flavonoid-rich foods may blunt breast cancer risk tied to genetics
By: Tarun Sai Lomte From: news-medical.net A large prospective study links tea, apples, oranges, berries, and other flavonoid-rich foods with reduced breast cancer risk, including among women with elevated genetic susceptibility. In a recent ‘Article in Press’ study published in the journal npj Breast Cancer, researchers assessed the association between the flavodiet score (FDS), a measure of flavonoid-rich food intake, and …
Can Breast Cancer Cause You to Gain Weight?
From: healthline.com Key takeaways Weight gain is common during and after breast cancer treatment due to factors like chemotherapy side effects, fatigue limiting exercise, and treatments inducing menopause. Gaining weight after a breast cancer diagnosis can negatively impact outlook, quality of life, and increase the risk of other conditions. Higher body weight and increased fat cells can elevate estrogen and …
Intermediate PRRX1 Levels Drive Breast Cancer Metastasis Risk
By: Pooja Toshniwal Paharia From: azolifesciences.com Breast cancer’s most high-risk cells may be determined at the tumor’s origin, where a fine-tuned balance between invasion and growth dictates whether cancer spreads or remains dormant. A recent study published in Nature Communications suggests that the metastatic potential of breast cancer cells may be established far earlier than previously recognized, within the original tumor …
Breast cancer risk assessments: What to know
By: Banu Arun, M.D. From: mdanderson.org Whatever your question, odds are there’s an online resource that promises an answer. That means it’s just as easy to search ‘What should I make for dinner?’ as it is ‘What’s my breast cancer risk?’ As a breast medical oncologist, some of the same tools my team uses to clinically assess breast cancer risk can be accessed for free online. But just like finding any cancer information …
Left-Side Breast Cancer EBRT Linked to Minimal Long-Term Cardiovascular Risk
By: Mary Ellen Schneider From: cancertherapyadvisor.com External beam radiation therapy (EBRT) for left-sided breast cancer has limited long-term cardiovascular risks, according to results published in JAMA Network Open. The findings suggest that contemporary photon-based EBRT techniques that reduce mean radiation dose to the heart have resulted in lower cardiovascular risks than those historically associated with left-side breast cancer radiation treatment, …
Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers
Source: BMJ Group From: news-medical.net Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics. The strongest association was found for genes involved in the activation of natural killer cells, which serve …