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Quest for new cancer treatment crosses milestone

In Clinical Trials by Barbara Jacoby

Source: Rice University From: sciencedaily.com A cancer therapy has crossed a milestone in clinical trials, a major development in a decades-long quest to develop a treatment that destroys tumors without the debilitating side effects of chemotherapy, invasive surgery and radiation. A cancer therapy invented at Rice University has crossed a milestone in clinical trials, a major development in a decadeslong …

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Moths and magnets could save lives

In In The News by Barbara Jacoby

Source: Rice University SUMMARY: Rice University bioengineers have combined a virus that infects moths with magnetic nanoparticles to create a potential new therapy for inherited genetic diseases like muscular dystrophy, sickle cell, cystic fibrosis, spinal muscular atrophy and some forms of cancer. A new technology that relies on a moth-infecting virus and nanomagnets could be used to edit defective genes …

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Nanoshells could deliver more chemo with fewer side effects

In In The News by Barbara Jacoby

From: Rice News In vitro study verifies method for remotely triggering release of cancer drugs Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside cancer cells in laboratory cultures. The study by researchers at Rice University …

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Rice lab creates tough, but tender, cancer fighters

In In The News by Barbara Jacoby

Variations of anti-tumor agents prove effective in the lab against even drug-resistant cancers Rice University scientists have developed and evaluated analogs of potent anti-tumor agents known as epothilones using designs and methods that both improve their biological properties and simplify their manufacture. The substances introduced by Rice synthetic organic chemist K.C. Nicolaou are similar in their cancer-fighting mechanism to paclitaxel, …

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New cancer fighter synthesized: Thailanstatin A disrupts cancer by inhibiting DNA-editing machinery

In In The News by Barbara Jacoby

Provided by: Rice University From: http: phys.org Rice University scientists have synthesized a novel anti-cancer agent, Thailanstatin A, which was originally isolated from a bacterial species collected in Thailand. Thailanstatin A fights cancer by inhibiting the spliceosome, the machinery in the cell that edits messenger RNA after transcription from DNA but before its translation into proteins. Rice synthetic chemist K.C. …

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Nanotubes are beacons in cancer-imaging technique

In In The News by Barbara Jacoby

From: phys.org Bathing a patient in LED light may someday offer a new way to locate tumors, according to Rice University researchers The spectral triangulation system developed by Rice chemist Bruce Weisman and his colleagues is intended to pinpoint targeted cancer tumors tagged with antibody-linked carbon nanotubes. It is described in a paper in the Royal Society of Chemistry journal …

Rice’s K.C. Nicolaou sets sights on cancer-related drug discovery

In In The News by Barbara Jacoby

From: Rice University At an age when many people are thinking about retirement, Rice chemist K.C. Nicolaou is embarking on one of the biggest challenges of his professional career. Nicolaou, 67, an academic titan whose work has been cited more than 50,000 times, built his reputation with basic research. His lab specializes in reproducing nature’s most complex organic molecules, but …