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Pancreatic cancer patient in partial remission after experimental drug treatment

In Clinical Trials by Barbara Jacoby

By: Ronda Wendler From: mdanderson.org Allison Lippman was 30 years old when she was diagnosed with stage 4 pancreatic cancer. A new drug that targets her cancer’s genetic mutation has shrunk her tumors in half. Just before she was diagnosed with pancreatic cancer, Allison Lippman was on top of the world. She’d just celebrated her 30th birthday, been promoted at …

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CRUK tests drug combo for advanced pancreatic cancer

In Clinical Trials by Barbara Jacoby

From: pharmaphorum.com Cancer Research UK has announced it will study Plexxikon’s dual kinase inhibitor PLX7486 in combination with gemcitabine in advanced pancreatic cancer as part of its Combinations Alliance. The novel combination of drugs targets the process of nerve invasion, observed in over 80% of pancreatic ductal adenocarcinoma (PDAC) and is associated with tumour spread and severe pain. The PAGoDA …

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AACR 2019: Maintenance Rucaparib Treatment in BRCA- or PALB2-Mutated Pancreatic Cancer

In Clinical Trials by Barbara Jacoby

By: The ASCO Post From: ascopost.com Maintenance treatment with the PARP inhibitor rucaparib was well tolerated and showed activity among patients with advanced BRCA– or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, according to results from an interim analysis of an ongoing phase II clinical trial presented by Reiss Binder et al at the American Association for Cancer Research (AACR) Annual Meeting …

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Enzyme USP15 may have potential role in future treatment of various cancers

In In The News by Barbara Jacoby

Source: George Washington University From: sciencedaily.com Researchers at the George Washington University (GW) Cancer Center found that the enzyme USP15 could potentially lead to new treatments for breast and pancreatic cancer. Their findings were published in Nature Communications. “With this study, we validate the role of USP15 in maintaining genome stability and tumor suppression and inform novel treatments for breast …

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Chinese Tree Bark Being Used to Treat Pancreatic Cancer

In In The News by Barbara Jacoby

By: Ivanhoe Newswire From: nbcdfw.com Pancreatic cancer is one of the most difficult cancers to treat and few patients survive past five years. But researchers are finding new hope in an ancient remedy. Michael Gilkerson doesn’t miss a day on his treadmill. He says it gives him strength and motivation after being diagnosed with pancreatic cancer more than two years …

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Okayama University research: 3D tissue model offers insights into treating pancreatic cancer

In In The News by Barbara Jacoby

Source: Okayama University From: prnewswire.com Okayama University research: 3D tissue model offers insights into treating pancreatic cancer Researchers at Okayama University show how specific cells of the pancreas can facilitate cancer progression. Pancreatic cancer can be fatal. It is extremely difficult to treat partly because its precise growth mechanism is not clear. One of the characteristics of pancreatic cancer is …

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Rainforest vine compound kills resilient cancer cells

In In The News by Barbara Jacoby

By: Ana Sandoiu From: medicalnewstoday.com New research now published in the Journal of Natural Products shows that a vine compound is highly effective in the fight against treatment-resistant pancreatic cancer cells. Pancreatic cancer is notoriously difficult to treat, and the condition has a poor outlook. According to the American Cancer Society (ACS), the 5-year survival rate for people with early-stage …

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Cancer drug from Kansas company can be tested on humans, FDA says. It’s made of lilies

In Clinical Trials by Barbara Jacoby

By: Lisa Gutierrez From: kansascity.com The Food and Drug Administration has approved human clinical testing for a new cancer drug created by a company based in the town of Sterling, Kansas — population 2,200, right in the middle of the state. The Genzada Pharmaceuticals drug is made from a flower native to the Middle East — described as “a black …

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New Drug Discovery for Pancreatic Cancer

In In The News by Barbara Jacoby

Source: University of Houston Drug for Pancreatic Cancer Developed by College of Pharmacy Researchers Heralds a new strategy for fighting cancer: Drugs that target two genes at a time A breakthrough treatment for highly aggressive and commonly fatal pancreatic cancer is on the horizon, reports a University of Houston researcher who has developed a new medicine that can inhibit two …

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This ‘metastasis-blocking’ compound may stop the spread of cancer

In In The News by Barbara Jacoby

By: Catharine Paddock PhD From: medicalnewstoday.com Using a new approach, scientists have located a compound that stops the spread of breast, pancreatic, and prostate cancers in mice. The compound — which they call metarrestin — destroys a unique structure inside the nucleus of cancer cells that can spread and form new tumors. A paper on the work — in which researchers from the National Institutes …