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Non-traditional gene fusions in luminal breast cancer: A new target for therapy

In In The News by Barbara Jacoby

Source: Oncotarget From: news-medical.net A new editorial paper was published in Oncotarget’s Volume 14 on June 12, 2023, entitled, “Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?” A vast majority of breast cancers (~70%) are estrogen receptor-alpha positive (ER+), for which endocrine therapy is the common treatment. However, recurrence often occurs leading to tumor progression, metastasis and …

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TONSL gene could be a new target for breast cancer treatment

In In The News by Barbara Jacoby

Source: Indiana University School of Medicine From: news-medical.net While trying to understand what initiates breast cells to become cancerous, researchers at the Vera Bradley Foundation Center for Breast Cancer Research at Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a new target for breast cancer treatment. “When comparing healthy breast tissue and cancerous cells, we wanted to …