Source: Business Wire From: apnews.com Seattle Genetics, Inc. (Nasdaq:SGEN) today announced it has completed the submission of a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for tucatinib. This NDA requests FDA approval of tucatinib in combination with trastuzumab and capecitabine for treatment of patients with locally advanced unresectable or metastatic HER2-positive breast cancer, including patients …
Tucatinib ‘game changing’ against HER2+ breast cancer, especially with brain metastases
Source: University of Colorado Anschutz Medical Campus From: eurekalert.org Phase III clinical trial results reported today in the New England Journal of Medicine and presented concurrently at the San Antonio Breast Cancer Symposium (SABCS) 2019 show the combination of the investigational drug tucatinib with standard of care treatment including the drugs trastuzumab and capecitabine nearly tripled one-year progression-free survival (33 …
Metastatic Breast Cancer Alliance Announces Release of MBC Connect 2.0
From: PR Newswire National Nonprofit’s Updated Mobile App and Online Platform will Identify Potential Clinical Trial Matches for Patients The Metastatic Breast Cancer Alliance (MBCA), the largest coalition of nonprofit breast cancer organizations, pharmaceutical/biotech companies, and patient advocates in the U.S., today announced the release of MBC Connect 2.0. MBC Connect is an interactive, web- and mobile-friendly patient experience registry …
Can Immunotherapy Be Used for Metastatic Breast Cancer?
From: healthline.com What is Immunotherapy? Immunotherapy is a new area of cancer treatment. In recent years, this type of treatment has proven successful in increasing survival rates in people with certain types of cancer. This includes metastatic prostate cancer and metastatic lung cancer. Researchers have also been looking at immunotherapy for metastatic breast cancer. For some time, they didn’t agree …
Following NCCN Guidelines for Metastatic Breast Cancer Results in Lower Costs for Patients, According to New Study
Source: National Comprehensive Cancer Network From: prnewswire.com Research from the O’Neal Comprehensive Cancer Center at UAB finds patients treated outside of NCCN Guidelines recommendations had significantly higher direct costs A new study from the O’Neal Comprehensive Cancer Center at University of Alabama at Birmingham (UAB), published in the October 2019 issue of JNCCN—Journal of the National Comprehensive Cancer Network, finds …
All Patients With Metastatic Breast Cancer Should Undergo Germline Testing, Study Finds
By: Laura Joszt From: ajmc.com All patients with metastatic breast cancer should undergo genetic testing, according to a new study on the prevalence of pathogenic/likely pathogenic (P/LP) variants in patients with metastatic breast cancer. The results, published in JAMA Oncology, highlight that there is a high prevalence of P/LP variants among the group of patients with metastatic breast cancer, which could have …
Importance of ER+ Patient Profiling to Determine MBC Therapy Options
Source: AstraZeneca From: news-medical.net Cell receptors are special proteins found within and on the surface of certain cells that enable signals in the form of substances in the bloodstream to affect cell function. When a substance binds to the specific receptor designed to recognize it, the receptor will be activated, and a chain of events initiated to achieve the desired …
Hereditary Cancer Risk Variants Found in Significant Subset of Metastatic Breast Cancer Patients
By: Staff Reporter From: genomeweb.com Investigators from Johns Hopkins University School of Medicine and the Vanderbilt Ingram Cancer Center have demonstrated that there is a potential benefit to doing widespread hereditary cancer risk testing in individuals with metastatic breast cancer. “[O]ur results provide evidence to support genetic testing for inherited cancer predisposition among all patients with metastatic breast cancer, because …
Resource Directory Built for Metastatic Breast Cancer Community
Source: GlobeNewswire From: finance.yahoo.com Directory supports patients’ specific needs in a fast and user-friendly manner Patient Advocate Foundation (PAF) has launched the Metastatic Breast Cancer Resource Directory, a new patient-friendly search tool designed to provide critical nonprofit, community and government resources that address the unique needs of the breast cancer and metastatic breast cancer community. This tool helps users quickly …
Breast Cancer Drug Available on CDF
A potentially life-extending drug combination for some people with advanced breast cancer will be made available on England’s Cancer Drugs Fund (CDF) following a recommendation by the National Institute for Health and Care Excellence (NICE). The draft guidance recommended ribociclib (Kisqali, Novartis) with fulvestrant (Faslodex, AstraZenica) as an option for people with hormone receptor-positive, human epidermal growth factor receptor 2 …