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‘Evil’ protein may be key in common breast cancer

In In The News by Barbara Jacoby

Source: University of Arizona From: futurity.org New research untangles some of the mysteries of a protein called EVL (pronounced “evil”), which may reduce the ability of a common kind of breast cancer to spread to other parts of the body. About 80 percent of all breast cancers are estrogen receptor-positive, in which estrogen fuels cancer growth. The new discovery could have …

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Breast cancer: Protein that drives metastasis uncovered

In In The News by Barbara Jacoby

By: Ana Sandoiu From: medicalnewstoday.com New research published in the journal Oncogene uncovers a protein that helps breast cancer to spread. The findings may lead to new therapies for invasive breast cancer. Despite many public awareness campaigns and scientific advances, breast cancer remains the second leading cause of cancer-related mortality in women, after lung cancer. Breast cancer deaths occur due …

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Is this the key to stopping cancer from spreading?

In In The News by Barbara Jacoby

By: Tim Newman From: medicalnewstoday.com When a tumor migrates to another part of the body, it makes cancer much more difficult to beat. A recently published study, investigating a metabolite called 20-HETE, gives new insight into this process and how it might be stopped. Cancer’s ability to metastasize – move through the body and take root in a distant location …

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Scientists find protein that regulates skin cancer spread

In In The News by Barbara Jacoby

By AFP From: ewvision.co.ug Scientists have pinpointed a cancer protein which controls the disease’s spread from the skin to other organs, and proposed Wednesday that blocking it may be an effective treatment. Working with mice genetically engineered to develop human skin cancers, the team discovered that the protein plays a key role promoting — or inhibiting — metastasis, the spread …

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Tel Aviv University Research Reveals How Melanoma Spreads to Other Organs in the Body

In In The News by Barbara Jacoby

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. According to a paper published today in the journal Nature Cell Biology, the scientists discovered that before spreading to other organs, a melanoma tumor sends out tiny vesicles containing molecules of microRNA. These induce morphological changes in …

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How breast cancer cells slide to metastasis

In In The News by Barbara Jacoby

Source: Cell Press From: sciencedaily.com The spreading of cancer cells from one part of the body to another, a process known as metastasis, is the leading cause of death among cancer patients. A study published April 26 in Biophysical Journal now reveals why some cancer cells may be more metastatic than others. The findings show that breast cancer cells spread …

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University researchers reveal key protein structure for cancer spread

In In The News by Barbara Jacoby

By: Irene Park From: michigandaily.com A University of Michigan research team led by John Tesmer, professor of pharmacology and biological chemistry, published a study earlier this month on a structure of a protein that might be important for preventing the spread of cancer throughout the body. Metastasis is the spread of the primary cancer from its original location to other parts of …

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Migrating cancer cells alter bone tissue to form tumors

In In The News by Barbara Jacoby

By: Catharine Paddock PhD From: medicalnewstoday.com Most people who die from cancer die from metastatic disease – where tumor cells migrate from the original site and start growing tumors in other parts of the body, such as bone. Now, new research reveals fresh clues on how migrating cancer cells alter bone tissue to make it suitable for tumor growth. The …

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Hedgehog signaling pathway for breast cancer identified

In In The News by Barbara Jacoby

From: http://medicalxpress.com Molecules called long non-coding RNAs (lncRNAs) have been implicated in breast cancer but exactly why they cause metastasis and tumor growth has been little understood…until now. Scientists at The University of Texas MD Anderson Cancer Center report that hedgehog, a unique cell signaling pathway known to contribute to many types of cancer, may be behind breast cancer metastasis. …

Device invented at Johns Hopkins provides up-close look at cancer on the move

In In The News by Barbara Jacoby

By: Phil Sneiderman From: jhu.edu Johns Hopkins engineers have invented a lab device to give cancer researchers an unprecedented microscopic look at metastasis, the complex way that tumor cells spread through the body, causing more than 90 percent of cancer-related deaths. By shedding light on precisely how tumor cells travel, the device could uncover new ways to keep cancer in …