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Roche drug is third to win biomarker-driven cancer approval from FDA

In Clinical Trials by Barbara Jacoby

By: Alaric DeArment From: medcitynews.com Another drug designed to treat cancer patients based on a genetic driver rather than where tumors occur in the body has received approval from the Food and Drug Administration. The FDA on Thursday granted Swiss drugmaker Roche’s Rozlytrek (entrectinib) approval for ROS1-positive non-small cell lung cancer and accelerated approval for solid tumors with NTRK gene …

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AstraZeneca’s flagship Tagrisso helps lung cancer patients live longer in pivotal study

In Clinical Trials by Barbara Jacoby

By: Natalie Grover From: endpts.com AstraZeneca is off to a good start in August. After its PARP inhibitor Lynparza scored in a prostate cancer trial earlier this week, the British drugmaker on Friday disclosed that its star cancer drug Tagrisso helped patients with a certain type of lung cancer live longer in a late-stage study. The overall survival data follows …

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Amgen Plans Pivotal Lung Cancer Trial For Its Pipeline Star

In Clinical Trials by Barbara Jacoby

Source: Andrew Dunn, BiotechDive From: pharmavoice.com Amgen stole the show at this year’s annual meeting of the American Society of Clinical Oncology with promising early data from a cancer drug designed to target KRAS mutations, an elusive target that’s frustrated decades of research efforts. Now, the biotech plans to soon advance the drug into a Phase 2 study in lung …

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Mesothelioma Victims Center Now Urges a US Navy Veteran with Mesothelioma or Asbestos Exposure Lung Cancer to Call Them

In In The News by Barbara Jacoby

Source: Mesothelioma Victims Center From: prnewswire.com Mesothelioma Victims Center Now Urges a US Navy Veteran with Mesothelioma or Asbestos Exposure Lung Cancer to Call Them for Direct Access to Attorney Erik Karst to Discuss the Value of Their Compensation Claim—Especially If the Veteran Was Stationed at Norfolk-Pearl Harbor or San Diego The Mesothelioma Victims Center’s number one goal is making …

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Immunotherapy for lung cancer: Researchers working to broaden its reach

In Clinical Trials by Barbara Jacoby

By: Scott Merville From: mdanderson.org Immunotherapy drugs have produced promising results in cancers like melanoma and leukemia, yet the drugs only work for 20 percent of lung cancer patients. MD Anderson researchers are working to change that. Immunotherapy drugs that free the immune system to attack cancer have provided durable responses for about 20 percent of lung cancer patients, which …

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Heat Biologics Presents Interim Phase 2 Lung Cancer Data on HS-110 + Nivolumab

In Clinical Trials by Barbara Jacoby

At ASCO-SITC Clinical Immuno-Oncology Symposium From: digitaljournal.com – Preliminary data suggests the addition of HS-110 to Nivolumab may restore responsiveness to treatment after tumor progression on prior checkpoint inhibitor therapy – Median overall survival not yet reached with median follow up of 14.4 months in Cohort A – Improved survival observed in patients with low CD8+ “cold” tumor at baseline …

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Racial disparities in US cancer deaths are shrinking, study finds

In In The News by Barbara Jacoby

Posted By: CNN Wire From: wtvr.com Racial disparities in cancer deaths between black and white patients in the United States are receding — but more progress is needed to completely close the gap for some cancer types and age groups, according to a new study. Among men, the overall cancer death rate was 47% higher for blacks than for whites …

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Breast cancer drugs could help treat therapy-resistant lung cancers

In Clinical Trials by Barbara Jacoby

Source: PTI | London From: theweek.in A class of drugs used to treat certain breast cancers could help fight lung cancers A class of drugs used to treat certain breast cancers could help fight lung cancers that have become resistant to targeted therapies, according to a study conducted in mice. The study, published in the journal Cell Reports, found that …

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New insight into why malaria drugs work against some cancers could boost drug development

In Clinical Trials by Barbara Jacoby

By: Arlene Weintraub From: fiercebiotech.com There are currently about 20 clinical trials underway evaluating a class of malaria drugs known as chloroquines in several tumor types, including breast cancer, lung cancer and multiple solid tumors, according to ClinicalTrials.gov. Anti-malarial drugs, in fact, have long been of interest in the oncology community because of their ability to shrink some cancers. But …

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New virus could help destroy cancer

In In The News by Barbara Jacoby

By: Chiara Townley From: medicalnewstoday.com A new study examines the behavior of a cancer-killing virus that fits tumor cells perfectly and leaves healthy cells intact. Cancer is a chronic disease that kills millions of people worldwide. According to the World Health Organization (WHO), cancer is the second leading cause of death globally and is likely to be responsible for more …