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Breast Cancer Becomes Vulnerable to Immune Cells Through DDR1 Deactivation

In In The News by Barbara Jacoby

From: genengnews.com Immune exclusion, or the lack of immune cells in the vicinity of cancer cells, predicts poor patient outcomes in multiple cancers, including triple-negative breast cancer (TNBC). Now, researchers have identified a key molecule, discoidin domain receptor 1 (DDR1), that prevents immune cells from entering tumors and killing the cancer cells inside through the formation of the extracellular matrix (ECM). …