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Breast cancer drug approved for Australia

In Clinical Trials by Barbara Jacoby

By: AAP From: 9news.com.au Kate Harper wants to be around to watch her two young twin sons grow up. That’s why, after grappling with the feeling of helplessness that came with being diagnosed with breast cancer, she made a commitment. “I said right from the start – and my husband’s in agreement as well – that we would attack everything …

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Subcutaneous Herceptin Combo Therapy for Certain Breast Cancer Patients Granted FDA Approval

In In The News by Barbara Jacoby

By: Jennifer Barrett From: pharmacytimes.com Officials with the FDA have approved trastuzumab and hyaluronidase-oysk (Herceptin Hylecta, Genentech) subcutaneous injection for certain patients with HER2-positive early and metastatic breast cancer, according to a press release. Trastuzumab and hyaluronidase-oysk is indicated for patients with early disease in combination with chemotherapy, and metastatic disease in combination with paclitaxel, or alone in patients who …

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Collaboration Promises Better, More Accurate Breast Cancer Diagnostics

In In The News by Barbara Jacoby

From: PR Newswire Data-sharing result s in an improved method of HER2 protein analysis which promises more accurate breast cancer diagnosis results. The Health Exchange Market, or T.H.E.M.™, together with LabCorp, Konica Minolta, Inc. University of Rochester, Penn State Hershey Medical Center and Lebanon VA Medical Center, has presented significant findings in breast cancer research at the 2018 San Antonio …

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uBiome Announces First Stage of Companion Diagnostic Development in Collaboration with Puma Biotechnology, Inc.

In In The News by Barbara Jacoby

From: prweb.com uBiome, the leader in microbial genomics, today announced the first stage of companion diagnostic development with Puma Biotechnology, Inc. (NASDAQ: PBYI) to investigate the role of the microbiome in adverse events related to neratinib treatment of patients with HER2-positive breast cancer. “This companion diagnostic and clinical trial work is an important part of the future of uBiome,” said …

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Puma Biotechnology Presents Results of Patient Reported Outcomes in Phase II CONTROL Trial of Neratinib in Extended Adjuvant Treatment of HER2-Positive Early Stage Breast Cancer

In Clinical Trials by Barbara Jacoby

From: businesswire.com Puma Biotechnology, Inc. (Nasdaq: PBYI), a biopharmaceutical company, is presenting updated results from a Phase II clinical trial of Puma’s drug neratinib at the 2018 San Antonio Breast Cancer Symposium (SABCS) that is currently taking place in San Antonio, Texas. The presentation entitled, “The impact of neratinib with or without anti-diarrheal prophylaxis on health-related quality of life in …

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New cancer vaccine may tackle HER2-positive tumors

In In The News by Barbara Jacoby

By: Ana Sandoiu From: medicalnewwstoday.com New research shows that a new cancer vaccine may be effective for treating a range of HER2-positive cancers, including the more aggressive HER2-positive breast cancer. Cancer that is human epidermal growth factor 2 (HER2)-positive holds too much of the protein on the surface of its cells. In HER2’s role as a growth factor, normal levels …

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FDA approves new treatment to reduce the risk of breast cancer returning

In In The News by Barbara Jacoby

Source: U.S. Food and Drug Administration From: PR Newswire The U.S. Food and Drug Administration today approved Nerlynx (neratinib) for the extended adjuvant treatment of early-stage, HER2-positive breast cancer. For patients with this type of cancer, Nerlynx is the first extended adjuvant therapy, a form of therapy that is taken after an initial treatment to further lower the risk of …

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EU Recommends Approval of Roche’s Pre-Surgery Breast Cancer Treatment

In In The News, Uncategorized by Barbara Jacoby

From: dddmag.com Roche announced that the EU Committee for Medicinal Products for Human Use (CHMP) has recommended that the European Commission approves the use of Perjeta (pertuzumab) in combination with Herceptin (trastuzumab) and chemotherapy for the neoadjuvant treatment (use before surgery) of adult patients with HER2-positive, locally advanced, inflammatory, or early stage breast cancer at high risk of recurrence. The EU filing was …

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Breast Cancer Cocktail Buys More Than a Year of Life

In In The News by Barbara Jacoby

By: Maggie Fox and Maren Shapiro From: nbcnews.com A cocktail of three breast cancer drugs buys patients an extra 16 months of life — a good news story so unusual, doctors have rushed to make it standard therapy, researchers said Wednesday. The combination includes two so-called magic bullet drugs plus standard chemotherapy. It helps patients with advanced HER-2 positive breast …

Aggressive breast cancer protein discovered

In In The News by Barbara Jacoby

From: nursingtime.net “A breakthrough by scientists could lead to a new treatment for one of the most aggressive forms of breast cancer,” the Mail Online reports. Researchers have identified a protein called integrin αvβ6, which may help trigger the spread of some types of breast cancer. Up to a third of breast cancers are HER2-positive cancers. These are cases of …