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Breast cancer: Reducing this amino acid could make drugs more effective

In In The News by Barbara Jacoby

By: Catharine Paddock PhD From: medicalnewstoday.com Leucine, an amino acid that the body needs for making protein, appears to have a surprising role in the development of resistance to tamoxifen in breast cancer that tests positive for the estrogen receptor. Scientists from Harvard Medical School, in Boston, MA, recently made this “unexpected” discovery about estrogen receptor-positive (ER-positive) breast cancer in …

New drug candidate from Vivolux starves cancer cells – clinical study due to begin shortly

In In The News by Barbara Jacoby

Vivolux AB, a drug discovery company specialized in cancer treatment, announced today that data that forms the basis for one of the company’s promising projects has been published in the journal Nature Communications. Researchers at Vivolux have discovered a novel cancer drug target. The drug candidate kills sleeping cell populations in regions of solid tumors that are less oxygenized – …

Novel noninvasive therapy prevents breast cancer formation in mice

In In The News by Barbara Jacoby

From: medicalxpress.com A novel breast-cancer therapy that partially reverses the cancerous state in cultured breast tumor cells and prevents cancer development in mice, could one day provide a new way to treat early stages of the disease without resorting to surgery, chemotherapy or radiation, a multi-institutional team led by researchers from the Wyss Institute of Biologically Inspired Engineering at Harvard …

Sanford-Burnham researchers identify new target for melanoma treatment

In In The News by Barbara Jacoby

by Patrick Bartosch Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) today announced the discovery that a gene encoding an enzyme, phosphoinositide-dependent kinase-1 (PDK1), plays an essential role in the development and progression of melanoma. The finding offers a new approach to treating this life-threatening disease. The team of researchers, led by Ze’ev Ronai, Ph.D., professor and scientific director of Sanford-Burnham …

Most Breast Cancer Deaths Occur in Younger, Unscreened Women: Study

In In The News by Barbara Jacoby

From: Drugs.com New breast cancer research reveals a significant death rate among women under 50 who forgo regular mammograms and casts doubt on recent screening guidelines from a U.S. panel of experts. The findings support the merit of regular mammograms, especially for younger women, said study researcher Dr. Blake Cady, professor emeritus of surgery at Harvard Medical School and Massachusetts …

New Clues to Fibromyalgia’s Causes

In In The News by Barbara Jacoby

From Drugs About half of fibromyalgia patients have damage to nerve fibers in their skin and other evidence of a disease called small-fiber polyneuropathy (SFPN), a small new study finds. Fibromyalgia is characterized by symptoms such as pain and tenderness, fatigue, and sleep and memory problems. The disorder has no known causes and few effective treatments. The study of 27 …

How to get healthy after the cancer treatments are done

In In The News by Barbara Jacoby

From the Washington Post By Christie Aschwanden No hospital sends a stroke patient home without a detailed plan to help them regain as much of their normal functioning as possible. Yet cancer patients are routinely released with no guidance on how to deal with the impairments that may linger after their treatment is done. “A lot of cancer survivors feel …

Aspirin Every Other Day May Lower Women’s Colon Cancer Risk

In In The News by Barbara Jacoby

From Drugs.com Taking a low-dose aspirin every other day may reduce the risk of colorectal cancer, according to a study that focused on nearly 40,000 women aged 45 and older. The protection does seem to take some time to surface, said researcher Nancy Cook, a professor of medicine at Brigham and Women’s Hospital and Harvard Medical School. “After 10 years, …