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Breast Cancer Becomes Vulnerable to Immune Cells Through DDR1 Deactivation

In In The News by Barbara Jacoby

From: genengnews.com Immune exclusion, or the lack of immune cells in the vicinity of cancer cells, predicts poor patient outcomes in multiple cancers, including triple-negative breast cancer (TNBC). Now, researchers have identified a key molecule, discoidin domain receptor 1 (DDR1), that prevents immune cells from entering tumors and killing the cancer cells inside through the formation of the extracellular matrix (ECM). …

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Aging breast tissue could set the stage for invasive breast cancer

In In The News by Barbara Jacoby

Source: University of Notre Dame From: sciencedaily.com The American Cancer Society estimates that 284,200 women will be newly diagnosed with breast cancer in 2021, and 43,600 will die of the disease — the second highest cause of cancer death in women. A woman’s risk of being diagnosed with breast cancer increases with age, but while scientists have long studied cellular …

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TGen-led study results suggest more accurate diagnostic for breast cancer

In Clinical Studies News by Barbara Jacoby

Source: The Translational Genomics Research Institute From: eurekalert.org Breast cancer, even at its initial stages, could be detected earlier and more accurately than current techniques using blood samples and a unique proteomics-based technology, according to findings of a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. Patrick Pirrotte, Ph.D., an Assistant Professor and …