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New Report Charts Dramatic Growth in the Global Clinical Trial Landscape for PD-1/L1 Immune Checkpoint Inhibitors

In Clinical Trials by Barbara Jacoby

From: cancerresearch.org 2,250 clinical trials are evaluating PD-1/L1 immune checkpoint inhibitors, an increase of 748 trials over the past year 1,716 trials are assessing regimens that combine PD-1/L1 immune checkpoints with other cancer therapies 240 drug targets are being evaluated in the current landscape, 75 more targets compared to a year ago Over 380,000 patient volunteers are required to fill …

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SWOG shares trio of studies at San Antonio breast cancer symposium

In Clinical Trials by Barbara Jacoby

From: eurekalert.org SWOG Cancer Research Network members will share the results of three studies at the San Antonio Breast Cancer Symposium, an international gathering of breast cancer physicians and researchers that starts today, with an estimated 7,500 attendees expected from more than 90 countries. SWOG is an international cancer clinical trials network funded by the National Cancer Institute (NCI), part …

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Immunotherapy Expands Treatment Options for Metastatic Bladder Cancer

In Clinical Trials by Barbara Jacoby

By: Danielle Ternyila From: targetedonc.com Several recent updates from clinical trials are transforming the treatment landscape for urothelial carcinoma across a variety of subtypes. The use of immunotherapy, in particular, provides patients who progress after standard platinum-based chemotherapy with new hope and a plethora of options. In the metastatic setting, there have been 5 immune checkpoint inhibitors approved by the …

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Building Disease Management Teams to Harness Clinical Trial Growth

In Clinical Trials by Barbara Jacoby

By: Mindy Waizer From: oncnursingnews.com The clinical trials program at the Lehigh Valley Cancer Institute (LVCI) grew exponentially in a short period of time. A great problem to have, certainly, but challenging to the organization. To ensure the successful absorption and growth of new trials, two nurses drove an initiative to reorganize LVCI’s framework of their current disease management teams. …

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9 things to know about CAR T-cell therapy

In Clinical Trials by Barbara Jacoby

By: Cynthia DeMarco From: mdanderson.org CAR T-cell therapy is a new type of cancer treatment offered at MD Anderson through clinical trials and FDA-approved standard of care cell therapy products. But what exactly is CAR T-cell therapy? And who should consider it? We spoke with Sattva Neelapu, M.D., to learn more. Here’s what he had to say. Let’s start with the …

Western Connecticut Health Network Site Launches Breast Cancer Clinical Trials through Collaboration with Memorial Sloan Kettering Cancer Center

In Clinical Trials by Barbara Jacoby

As part of a pioneering cancer-care collaboration between Norwalk Hospital and Memorial Sloan Kettering Cancer Center, clinical trials studying new breast cancer therapies are now open in Fairfield County. Four cutting-edge breast cancer clinical trials have launched at Norwalk Hospital, part of the Western Connecticut Health Network. The breast cancer clinical trials are an extension of Memorial Sloan Kettering Cancer …

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Study: Wearable fitness monitors useful in cancer treatment

In In The News by Barbara Jacoby

From: utsouthwestern.edu Wearable fitness trackers, such as Fitbits, that measure steps taken per day may be a useful tool to evaluate and help treat cancer patients, researchers at UT Southwestern’s Simmons Cancer Center have shown. A pilot study of older cancer patients found that they were willing to wear physical activity monitors (PAMs) for 10 weeks or more and used them correctly. …

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Keytruda Performs Well in Latest Lung Cancer Clinical Trials

In In The News by Barbara Jacoby

From: healthline.com The immunotherapy drug has been successful in treating other cancers and the latest trials provide hope for people battling lung cancer. When Edith Pelka was diagnosed with advanced non-small cell lung cancer last summer, the retired New York nurse, yoga instructor, and self-described “straight shooter” thought her life was over. “After the surgeon told me that my tumor …

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Is it time to say goodbye to ClinicalTrials.Gov?

In In The News by Barbara Jacoby

By: Zikria Syed From: medcitynews.com It is an exciting time in the pharmaceutical industry. According to industry organization PHRMA, there are currently more than 7,000 new medicines under development with many being first in class treatments. Digital technology combined with medicine, gene therapy and personalized medicine are driving a lot of this. However, to bring these treatments to market, clinical trials …

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Cancer clinical trials exclude many desperate patients – should that change?

In In The News by Barbara Jacoby

By: Aimee Swartz, Special To The Washington Post From: chicagotribune.com When 29-year-old Carly Bastiansen was diagnosed in January 2016 with advanced pancreatic cancer, doctors told her a clinical trial was her best shot at slowing the notoriously quick-killing and hard-to-treat disease. She found one that appeared promising and went through the screening process. But the trial would not accept her. …