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Concurrent Chemoradiotherapy Better for Painful Bone Metastases in Breast Cancer

In In The News by Barbara Jacoby

By: Colby Strong From: cancertherapyadvisor.com Concurrent chemoradiotherapy is tolerable and reduces pain better than radiotherapy alone for patients with breast cancer and painful bone metastases, according to research published in the Journal of Bone Oncology. The randomized, phase 2 study included 84 patients with breast cancer and painful bone metastases. The patients were randomly assigned to radiotherapy only (42 patients) …

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How Many Years of Aromatase Inhibitor Tx in Breast Cancer?

In In The News by Barbara Jacoby

By: Neil Osterweil From: medscape.com How long is long enough ― or too long ― when it comes to adjuvant aromatase inhibitor (AI) therapy for postmenopausal women with early-stage hormone receptor–positive (HR+) breast cancer? That’s a question that has been vexing oncologists for more than a decade, but final results from a large study now suggest that after an initial …

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SERDs Represent the Next Generation of ER-Targeting Therapy in Breast Cancer

In Clinical Studies News by Barbara Jacoby

By: Jason Harris From: onclive.com Selective estrogen receptor degraders are becoming increasingly important in the treatment of ER-positive metastatic breast cancer. Selective estrogen receptor degraders (SERDs) are becoming increasingly important in the treatment of ER-positive metastatic breast cancer (MBC), Erika P. Hamilton, MD, said during a presentation at the 20th Annual International Congress on the Future of Breast Cancer® East …

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UChicago Medicine enrolling patients in LymphBridge™ clinical study for surgical treatment of breast cancer-related lymphedema

In In The News by Barbara Jacoby

By: University of Chicago Medical Center From: newswise.com The University of Chicago Medicine has announced today that it is now enrolling patients in LymphBridge™, a randomized clinical study to evaluate a novel surgical treatment for addressing breast cancer-related lymphedema. This study is sponsored by Fibralign Corporation with funding provided by the National Cancer Institute (NCI) and being led by world-renowned …

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New drug could help in breast cancer fight, Scottish research finds

In Clinical Studies News by Barbara Jacoby

By: Craig Cairns From: thenational.scot A PROTEIN which helps breast cancer tumours survive could be targeted with a new type of drug that is already being tested for other cancers, research suggests The protein, known as MCL-1, helps breast cancer cells survive by hindering their natural ability to die. This process, called apoptosis, is the body’s way of getting rid …

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Changes detected in BRCA1 breast cells before they turn cancerous

In Clinical Studies News by Barbara Jacoby

From: cancerresearchuk.org A new study funded by Cancer Research UK has mapped out some of the earliest changes that occur in seemingly healthy breast tissue long before any tumours appear, which could have significant implications for the early detection of breast cancer. The paper, published today in Nature Communications(link is external), has discovered that before becoming cancerous, breast cells with the BRCA1 …

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Medifirst Solutions Announces a Clinical Study for a Breast Cancer Diagnostic Medical Device

In Clinical Studies News by Barbara Jacoby

Source: Globe Newswire From: biospace.com MEDIFIRST SOLUTIONS, INC. (OTC: MFST) (the “Company” or “Medifirst”), is pleased to announce it is a Sponsor and Collaborator for an upcoming breast cancer clinical study for real-time margin detection. About 1 in 8 U.S. women will develop invasive breast cancer over the course of her lifetime. Besides skin cancer, breast cancer is the most commonly diagnosed …

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Estradiol Challenge Test ‘Highly Predictive’ of Response to Endocrine Therapy in Patients With ER-Positive Breast Cancer

In Clinical Studies News by Barbara Jacoby

By: Leah Lawrence From: cancertherapyadvisor.com The use of a positron emission tomography (PET)-based estradiol challenge test was found to be highly predictive of response to endocrine therapy in women with estrogen-receptor (ER)-positive breast cancer. In the phase 2 study (NCT02455453), data from which were published in Nature Communications, the investigators measured the responses to endocrine therapy by monitoring the change …

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Study Identifies Breast Cancer Risk and Disease-Causing Mutations in Women Over 65

In Clinical Studies News by Barbara Jacoby

By: Hannah Slater From: cancernetwork.com Women with onset of breast cancer over age 65 typically do not qualify for genetic testing, however this study demonstrated that frequency of pathogenic variants and risk of breast cancer is not negligible in this patient population. A study presented at the American Society of Human Genetics 2020 Virtual Meeting provided estimates of prevalence and …

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Early-Onset Breast Cancer Possibly Linked to Preeclamptic Pregnancy, High Birth Weight

In Clinical Studies News by Barbara Jacoby

By: Maggie L. Shaw From: ajmc.com With little research on the subject, the investigators sought out a connection between certain perinatal factors and risk of young-onset breast cancer in a sister-matched case-control study. Certain perinatal factors have been shown to possibly exert influence over an increased risk of developing early-onset breast cancer, reported a study published in Breast Cancer Research. …