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New Experimental Therapy CAR NKT-Cells Tested In Cancer Patients For The First Time

In Clinical Trials by Barbara Jacoby

  By: Victoria Forster From: forbes.com CAR T-cells are becoming somewhat of a household name, but a new phase I trial is, for the first time, using CAR ‘NKT’ cells, featuring genetic modification of a different immune cell, natural killer cells. Natural killer T-cells have long been known to be important in mediating the immune system’s response to cancer, targeting both tumor …

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Familial breast cancer may be preventable by medication: Austrian experts

In Clinical Trials by Barbara Jacoby

Source: Xinhua From: xinhuanet.com Breast cancer passed down in families may be preventable by the medication Denosumab, which is undergoing a five-year study in Austria. The Austrian Breast and Colorectal Cancer Study Group is leading the work as it examines the drug’s effectiveness on 2,950 patients with a hereditary disposition to this particular form of cancer, according to an Austria …

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Women with breast cancer sought for nationwide weight loss study

In Clinical Trials by Barbara Jacoby

Researchers: Can losing weight prevent recurrence of breast cancer? Beaumont researchers are seeking women with breast cancer for a national research study. Investigators hope to learn if weight loss decreases the likelihood of a recurrence of breast cancer. The research is known as the BWEL study, or Breast Cancer Weight Loss Study. “Previous studies have found that women who are …

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Oak Park Woman Benefits from Clinical Trial for Multiple Myeloma

In Clinical Trials by Barbara Jacoby

By: Elizabeth Katz From: thejewishnews.com Barbara Robins, 75, of Franklin has lived a full life, working as a financial adviser while also keeping herself in optimum health and enjoying her friends, travel and art. Because she’s kept herself so healthy and active, a diagnosis of multiple myeloma in 2015 stopped her in her tracks. “It was completely a surprise,” she …

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UH Cancer Center, HMSA collaborate to fight breast cancer

In Clinical Trials by Barbara Jacoby

By: Nana Ohkawa From: hawaii.edu The University of Hawaiʻi Cancer Center is working with the Hawaiʻi Medical Service Association (HMSA) to conduct a first-of-its-kind clinical trial that could lead to less anxiety for patients with metastatic breast cancer, improved quality of life for patients and their families and lower costs for the community. These changes would result from optimizing the …

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Cancer: ‘Off-the-shelf’ stem cell treatment enters clinical trial

In Clinical Trials by Barbara Jacoby

By: Yella Hewings-Martin PhD From: medicalnewstoday.com In a first-of-its-kind trial in the United States, researchers are testing a stem cell-derived natural killer cell immunotherapy in people with incurable cancer. Cancer follows heart disease as the second biggest killer worldwide. In the United States, an estimated 606,880 people will die due to cancer in 2019. With the advent of immunotherapy, researchers …

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Rakuten Medical’s ASP-1929 photoimmunotherapy for head and neck cancers to be designated under the Sakigake Designation System for its potential innovativeness and effectiveness

In Clinical Trials by Barbara Jacoby

Source: Rakuten Medical, Inc. From: prnewswire.com Based on its exclusive license related to photoimmunotherapy, Rakuten Medical Inc., which is developing a cancer therapy to target cancer cells, announced that ASP-1929 received Sakigake designation under the Sakigake Designation System*, which is a Fast Track designation from the Japanese Ministry of Health, Labour, and Welfare as a treatment for head and neck …

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UC San Diego Health treats 1st cancer patient with stem-cell derived natural killer cells

In Clinical Trials by Barbara Jacoby

Source: University of California-SanDiego From: eurekalert.org After 10 years in remission, Derek Ruff’s cancer returned, this time as stage IV colon cancer. Despite aggressive rounds of chemotherapy, palliative radiotherapy and immunotherapy, his disease progressed. In February 2019, as part of a phase I clinical trial at Moores Cancer Center at UC San Diego Health, Ruff became the first patient in …

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Northern Biologics Reports Initial Phase I Data for MSC-1 at AACR

In Clinical Trials by Barbara Jacoby

From: businesswire.com Northern Biologics Inc., a company focused on developing first-in-class immuno-oncology products, today announced the presentation of initial results from the Phase I trial of their lead antibody, MSC-1, at the American Association for Cancer Research meeting in Atlanta, Georgia. MSC-1 is a humanized antibody against a soluble cytokine called LIF (see “About LIF” below). LIF plays a multi-faceted …

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Yuhan Corp and Sorrento Therapeutics Announce Completion of Phase 1 Clinical Study of Anti-PD-L1 Antibody IMC-001

In Clinical Trials by Barbara Jacoby

Source: Sorrento Therapeutics, Inc. From: apnews.com Yuhan Corporation (000100.KS; Yuhan) and Sorrento Therapeutics, Inc. (Nasdaq: SRNE) announced today that ImmuneOncia, a joint venture formed in September 2016, has completed the Phase 1 study of IMC-001 (also known as STI-3031), a fully human anti-PD-L1 monoclonal antibody (mAb) immune checkpoint inhibitor. This Phase 1 dose-escalation study, approved by the South Korean Ministry …