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Quest for new cancer treatment crosses milestone

In Clinical Trials by Barbara Jacoby

Source: Rice University From: sciencedaily.com A cancer therapy has crossed a milestone in clinical trials, a major development in a decades-long quest to develop a treatment that destroys tumors without the debilitating side effects of chemotherapy, invasive surgery and radiation. A cancer therapy invented at Rice University has crossed a milestone in clinical trials, a major development in a decadeslong …

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Study of SM-88 Shows Promising Results in Advanced Pancreatic Cancer

In Clinical Trials by Barbara Jacoby

By: Gina Columbus From: targetedonc.com The investigational agent SM-88 demonstrated promising survival in the phase II TYME-88-Panc study in patients with advanced pancreatic cancer.1,2 The oral modified dysfunctional tyrosine induced a median overall survival (OS) of 6.4 months in patients. The RECIST clinical benefit rate (CBR) of stable disease (SD) or better was 44% with available imaging, and there was a 92% …

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MetVital, Inc. Announces FDA Clearance of Investigational New Drug (IND) Application for AEO for Phase 2 testing for Glioblastoma Multiforme

In Clinical Trials by Barbara Jacoby

From: finance.yahoo.com MetVital, Inc., a biopharmaceutical company developing small molecule modulators of glutamate metabolism for the treatment of diseases with significant unmet medical need and commercial potential, today announces that the U.S. Food and Drug Administration (FDA) has notified MetVital that it may proceed with its clinical investigation of “Anhydrous Enol-Oxaloacetate” (AEO) as a potential treatment for patients with Glioblastoma …

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6 months treatment with Herceptin is as good as 12 months for preventing breast cancer return

In Clinical Trials by Barbara Jacoby

By: Peter Thorley, University of Warwick From: medicalxpress.com A new study co-led by the University of Warwick Clinical Trials Unit has shown that shortening the duration of a therapy for breast cancer patients does not increase the risk of their cancer returning. The majority of clinical trials in cancer assess either new treatments or additional treatments to the current standard …

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Therapeutics Discovery division advances novel small-molecule to clinic

In Clinical Trials by Barbara Jacoby

By: Clayton R. Boldt, Ph.D. From: mdanderson.org The Therapeutics Discovery division at MD Anderson Cancer Center has advanced a new small-molecule inhibitor of cancer metabolism to Phase I clinical trials. This new drug candidate marks the fourth novel therapeutic brought from concept to clinical trial by Therapeutics Discovery, a drug-discovery engine built within the walls of MD Anderson to eliminate …

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New Experimental Therapy CAR NKT-Cells Tested In Cancer Patients For The First Time

In Clinical Trials by Barbara Jacoby

  By: Victoria Forster From: forbes.com CAR T-cells are becoming somewhat of a household name, but a new phase I trial is, for the first time, using CAR ‘NKT’ cells, featuring genetic modification of a different immune cell, natural killer cells. Natural killer T-cells have long been known to be important in mediating the immune system’s response to cancer, targeting both tumor …

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Familial breast cancer may be preventable by medication: Austrian experts

In Clinical Trials by Barbara Jacoby

Source: Xinhua From: xinhuanet.com Breast cancer passed down in families may be preventable by the medication Denosumab, which is undergoing a five-year study in Austria. The Austrian Breast and Colorectal Cancer Study Group is leading the work as it examines the drug’s effectiveness on 2,950 patients with a hereditary disposition to this particular form of cancer, according to an Austria …

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Women with breast cancer sought for nationwide weight loss study

In Clinical Trials by Barbara Jacoby

Researchers: Can losing weight prevent recurrence of breast cancer? Beaumont researchers are seeking women with breast cancer for a national research study. Investigators hope to learn if weight loss decreases the likelihood of a recurrence of breast cancer. The research is known as the BWEL study, or Breast Cancer Weight Loss Study. “Previous studies have found that women who are …

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Oak Park Woman Benefits from Clinical Trial for Multiple Myeloma

In Clinical Trials by Barbara Jacoby

By: Elizabeth Katz From: thejewishnews.com Barbara Robins, 75, of Franklin has lived a full life, working as a financial adviser while also keeping herself in optimum health and enjoying her friends, travel and art. Because she’s kept herself so healthy and active, a diagnosis of multiple myeloma in 2015 stopped her in her tracks. “It was completely a surprise,” she …

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UH Cancer Center, HMSA collaborate to fight breast cancer

In Clinical Trials by Barbara Jacoby

By: Nana Ohkawa From: hawaii.edu The University of Hawaiʻi Cancer Center is working with the Hawaiʻi Medical Service Association (HMSA) to conduct a first-of-its-kind clinical trial that could lead to less anxiety for patients with metastatic breast cancer, improved quality of life for patients and their families and lower costs for the community. These changes would result from optimizing the …