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Vitamin deficiency ‘puts cancer cells into hibernation’

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Source: University of Salford From: sciencedaily.com A new potential therapeutic agent, diphenyleneiodonium chloride (DPI), effectively switches off cancer stem cells, preventing their proliferation, researchers report. “It’s extraordinary; the cells just sit there as if in a state of suspended animation,” explains Professor Michael Lisanti, Chair of Translational Medicine and lead investigator. The discovery is significant because the drug halts the …

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Immunotherapy trial treatment getting results for cancer patients

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By: Kirstin O’Connor From: clickorlando.com Florida Hospital first site in nation for clinical trial Karen Bierer was given two years to live after she was diagnosed with ovarian cancer. The 70-year-old is one of nearly 21,000 women in the U.S. diagnosed with the deadly disease every year, according to the Centers for Disease Control and Prevention. Chemotherapy and radiation were nothing new …

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Personalized cancer treatment 2.0: new combination strategy developed

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Source: Netherlands Cancer Institute Tumors often comprise groups of cancer cells that show differential drug sensitivities. This is one of the reasons that initially effective treatments usually do not lead to long-term benefit in patients. Researchers from the Netherlands Cancer Institute in Amsterdam, in collaboration with the international biotechnology company Genmab A/S, have now developed a new strategy to tackle …

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First treatment approved for breast cancer with BRCA genetic mutation

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By: Laurie McGinley From: washingtonpost.com The Food and Drug Administration on Friday cleared the first treatment for patients with advanced breast cancer caused by BRCA mutations, which are genetic defects that raise the risk of malignancies. The drug, called Lynparza, already is approved for certain patients with advanced ovarian cancer associated with the same mutations. Richard Pazdur, director of the …

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Distrust In Health-Care System Might Prevent Breast Cancer Patients From Getting Recommended Care

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By: Rita Rubin From: forbes.com People who distrust the health-care system are less likely to follow doctor’s orders, suggests a new study of breast cancer patients. The thing is, the women in this study who opted out of prescribed follow-up treatments didn’t necessarily distrust their doctors. They distrusted the faceless hospitals, laboratories, insurance companies and drug makers that constitute the …

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A radical new cancer treatment is to be tested using cells from cancer survivors

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By: Colin Fernandez From: dailymail.co.uk A radical new cancer treatment inspired by patients who seem to ‘shrug off’ the disease could be tested next year. The technique uses potent cancer-killing cells from people with the strongest immune systems. These ‘neutrophil’ cells – which form part of the body’s first line of defence – are then multiplied millions of times and …

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A group of cancer doctors discovered a way to slash the cost of expensive pills by up to 75%, but they’ve hit a wall

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By: Lydia Ramsey From: businessinsider.com The cost of certain cancer drugs has gotten high, often to more than $100,000 a year. To combat that, researchers are looking for treatments that could be taken at a lower dose, so long as they’re taken with food. But finding the funding to study lower doses hasn’t been easy. Dr. Mark Ratain, the chief …

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A New Way to Kill Cancer Cells… By Using an Old Drug

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By: Teodora Zareva From: bigthink.com A team of scientists from Duke University’s Cancer Institute have published a paper in the journal Science Translational Medicine outlining the mechanisms of a new cancer therapy that uses a modified poliovirus (PVS-RIPO). The poliovirus attacks cancer tumors and activates an inflammation process, which in turn enables the body’s own immune system to target the cancer …

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Blacks, Elderly Missing From U.S. Cancer Clinical Trials

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From: drugs.com Four out of five participants in cancer clinical trials are white, a discrepancy that calls into question whether other races and ethnicities are receiving good cancer treatment, researchers say. Women and the elderly also are underrepresented in clinical trials, according to the new findings. Prior studies have shown that the effectiveness of cancer treatment can vary based on …