By: Mary Ellen Schneider From: cancertherapyadvisor.com Pyrotinib plus trastuzumab and docetaxel outperformed trastuzumab and docetaxel alone as an initial treatment for HER2-positive metastatic breast cancer, according to findings published in the BMJ. The final analysis of the phase 3 PHILA taril (NCT03863223) demonstrated significant improvements in both progression-free survival (PFS) and overall survival (OS). “Pyrotinib, a small molecule, irreversible, pan-HER …
From This Breast Cancer Survivor: I Remember THE Day
View PostStrategy to detect infections early after breast reconstruction may have ‘broad impact’
By: Mark Leiser From: healio.com Metabolites in tissue fluid offer important clues that could help predict infection risk among women who undergo breast reconstruction after cancer. Metabolites — small molecules created or broken down during cellular processes such as energy production or cell signaling — include specialized small molecules produced by bacterial pathogens. Analyses of metabolite patterns among women who …
A Blood Test May Better Tailor Breast Cancer Treatment for Older Women
From: upmc.com For women age 70 and over with a common form of breast cancer, determining “the right size” of treatment can be challenging, in part because clinicians have limited tools to guide individualized treatment decisions. In a study published today in Clinical Cancer Research, scientists at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine found …
But those who hope in the Lord will renew ..
But those who hope in the Lord will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint. Isaiah 40:31 Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched readers worldwide. LetLifeHappen.com
Pumitamig Plus Chemo Drives Strong Responses Across PD-L1 Subgroups of Metastatic TNBC
By: Ashling Wahner From: onclive.com The VEGF/PD-L1–directed bispecific antibody pumitamig (BNT327/BMS986545) has been shown to restore immune activity and improve outcomes in patients with metastatic triple-negative breast cancer (TNBC), showing strong response rates even in patients with a PD-L1 combined positive score (CPS) lower than 10, according to Sarah Sammons, MD. Previously, data from a phase 1b/2 trial (NCT05918133) conducted …
Combination treatment benefits patients with advanced breast cancer that has spread to brain
From: mdanderson.org Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and trastuzumab, plus the chemotherapy drug, capecitabine, may improve symptoms and extend survival in some breast cancer patients with LM. The Phase II study, published today in Nature Cancer, included 17 female patients with newly diagnosed LM and HER2+ breast cancer. Median overall survival (OS) in those treated with the combination therapy increased from a historical average of 4.4 months to 10 months. …
Culturally tailored videos may help inform breast cancer screening
By: Amerigo Allegretto From: auntminnie.co Culturally adapted informational video may improve breast cancer knowledge among patients, suggest findings published March 13 in PEC Innovation. A 12-minute video intervention led to increased self-efficacy and mammography screening intention for a mostly Hispanic study population, wrote a team of researchers led by Priyanka Dadha, PhD, from Texas Tech University in El Paso. “The culturally …
Telehealth visits may help breast cancer patients stay on treatment
By: Sydney Barrilleaux, University of Georgia From: medicalxpress.com Staying in touch with doctors online could help breast cancer survivors keep up their cancer treatment, according to a recent study from the University of Georgia published in the Journal of Cancer Survivorship. After chemotherapy and surgery, most breast cancer survivors are prescribed oral endocrine therapy to prevent the disease from coming …